HitPredict

Interactor 1: MAFG (O15525)
Transcription factor MafG (V-maf musculoaponeurotic fibrosarcoma oncogene homolog G) (hMAF)
Gene: MAFG

Interactor 2: NF2L3 (Q9Y4A8)
Nuclear factor erythroid 2-related factor 3 (NF-E2-related factor 3) (NFE2-related factor 3) (Nuclear factor, erythroid derived 2, like 3)
Gene: NFE2L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 28514442, 33961781, 23661758, 20102225
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, peptide array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains bZIP_Maf~bZIP_Maf
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 162
Hs

1 694
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Last updated: 15 Jul 2024