Interactor 1: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1
Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.66 | 1.00 | 0.817 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 31980649, unassigned2173, 25036637 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDC37_M~Pkinase, CDC37_N~Pkinase |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
