HitPredict

Interactor 1: WDR46 (O15213)
WD repeat-containing protein 46 (WD repeat-containing protein BING4)
Gene: WDR46

Interactor 2: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TruB_C_2~WD40
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 514
+	Hs
		72748 B0UZZ8_HUMAN (1-610): 1.68e-168: 495: 99.84		DKC1_HUMAN (1-514): 0: 779: 100.00
+	Hs
		257980 NLE1_HUMAN (96-486): 2.45e-75: 250: 13.00		DKC1_HUMAN (1-514): 0: 779: 100.00
+	Hs
		257921 FBXW7_HUMAN (303-522): 1.21e-36: 147: 11.56		DKC1_HUMAN (1-514): 0: 779: 100.00
+	Hs
		257796 WDR5_HUMAN (390-531): 8.26e-15: 77.9: 6.25		DKC1_HUMAN (1-514): 0: 779: 100.00