HitPredict

Interactor 1: PDPK1 (O15530)
3-phosphoinositide-dependent protein kinase 1 (hPDK1) (EC 2.7.11.1)
Gene: PDPK1

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.638

Property	Details
Experiments	26186194, 28514442, 33961781, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 447
+	Hs
		182123 PDPK1_HUMAN (1-556): 0: 563: 100.00		WDR5_HUMAN (4-165): 6.22e-31: 123: 8.93
+	Dm
		1213409 AKT1_DROME (75-409): 2.54e-141: 423: 34.82		NLE_DROME (294-446): 9.59e-27: 114: 13.21
+	Hs
		609659 KAPCG_HUMAN (70-391): 1.4e-137: 404: 32.61		RACK1_HUMAN (266-445): 3.22e-20: 92.7: 16.30
+	Dm
		186204 AKT1_DROME (75-409): 2.54e-141: 423: 34.82		GBLP_DROME (12-167): 8.97e-09: 58.8: 13.04
+	Dm
		186250 PDPK1_DROME (72-235): 2.59e-48: 181: 52.12		GBLP_DROME (12-167): 8.97e-09: 58.8: 13.04