HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 758
+	Hs
		152556 KDM6A_HUMAN (1-1401): 0: 1681: 100.00		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		183137 KDM6A_HUMAN (1-1401): 0: 1681: 100.00		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		150088 UTY_HUMAN (1-1393): 0: 1402: 65.41		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		150104 UTY_HUMAN (1-1393): 0: 1402: 65.41		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		174574 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		174891 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		175053 OGT1_HUMAN (166-609): 5.45e-46: 183: 13.63		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		1057016 CDC23_HUMAN (134-642): 8.91e-16: 84.6: 11.21		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		672833 CDC27_HUMAN (96-315): 2.28e-11: 70.6: 22.75		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Dm
		1370278 Q9VSK6_DROME (233-614): 3.43e-16: 87: 11.22		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96