Protein: CARF
CDKN2A-interacting protein (Collaborator of ARF)

Gene: CARF, CDKN2AIP
Organism: Homo sapiens
Interactions: 152
UniProt ID: Q9NXV6

Gene Ontology (top 5):
GO:0001652 - granular component
GO:0002039 - p53 binding
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1429805

XRN2
5'-3' exoribonuclease 2

5

4

High-throughput

0.927

High

911412

IMA5
Importin subunit alpha-5

4

2

High-throughput

0.697

High

172237

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

3

4

High-throughput

0.667

High

321879

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

2

1

High-throughput

0.628

High

1090310

ELAV2
ELAV-like protein 2

2

2

High-throughput

0.628

High

1452146

H2AW
Core histone macro-H2A.2

2

2

High-throughput

0.628

High

686481

RL13
Large ribosomal subunit protein eL13

2

1

High-throughput

0.601

High

485462

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

3

High-throughput

0.584

High

589868

RFA2
Replication protein A 32 kDa subunit

2

1

High-throughput

0.584

High

696687

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

High-throughput

0.584

High

769349

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.584

High

1330264

ARF
Tumor suppressor ARF

2

1

Small-scale

0.576

High

397078

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

842875

CDN2A
Cyclin-dependent kinase inhibitor 2A

2

0

Small-scale

0.561

High

1028420

MDM2
E3 ubiquitin-protein ligase Mdm2

2

0

Small-scale

0.559

High

191840

MAGB2
Melanoma-associated antigen B2

2

2

High-throughput

0.549

High

224173

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

1

High-throughput

0.536

High

287170

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

8

High-throughput

0.536

High

521980

H14
Histone H1.4

1

4

High-throughput

0.536

High

913071

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

5

High-throughput

0.536

High

1009342

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

1027802

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

High-throughput

0.536

High

1097236

PAK2
Serine/threonine-protein kinase PAK 2

1

1

High-throughput

0.536

High

1114461

CUL3
Cullin-3

1

2

High-throughput

0.536

High

1137182

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

1

1

High-throughput

0.536

High

1148810

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

1156875

E2F4
Transcription factor E2F4

1

1

High-throughput

0.536

High

1168907

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

2

High-throughput

0.536

High

1307528

RBM45
RNA-binding protein 45

1

3

High-throughput

0.536

High

1314879

FANCM
Fanconi anemia group M protein

1

7

High-throughput

0.536

High

1395837

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

1

High-throughput

0.536

High

1437370

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.536

High

1447820

DDX21
Nucleolar RNA helicase 2

1

2

High-throughput

0.536

High

1452151

PURG
Purine-rich element-binding protein gamma

1

1

High-throughput

0.536

High

1452153

ABT1
Activator of basal transcription 1

1

1

High-throughput

0.536

High

1227577

A16L1
Autophagy-related protein 16-1

2

4

High-throughput

0.521

High

407723

S100B
Protein S100-B

1

0

High-throughput

0.513

High

533014

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

586348

ZEP1
Zinc finger protein 40

1

0

High-throughput

0.513

High

651726

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

0

High-throughput

0.513

High

774120

ADDA
Alpha-adducin

1

0

High-throughput

0.513

High

787804

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.513

High

860032

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

973609

RS11
Small ribosomal subunit protein uS17

1

0

High-throughput

0.513

High

1111317

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.513

High

1130866

RRP5
Protein RRP5 homolog

1

0

High-throughput

0.513

High

1228338

UTP25
U3 small nucleolar RNA-associated protein 25 homolog

1

0

High-throughput

0.513

High

1279240

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.513

High

1314803

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

0

High-throughput

0.513

High

1347613

NEIL3
Endonuclease 8-like 3

1

0

High-throughput

0.513

High

1371165

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

1

0

High-throughput

0.513

High

1404459

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1420696

FTO
Alpha-ketoglutarate-dependent dioxygenase FTO

1

0

High-throughput

0.513

High

1429466

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

0

High-throughput

0.513

High

1448898

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.513

High

1452145

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

1452152

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.513

High

1452155

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.513

High

1452157

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.513

High

64813

EPAB2
Embryonic polyadenylate-binding protein 2

1

1

High-throughput

0.489

High

186592

TRI18
E3 ubiquitin-protein ligase Midline-1

1

3

High-throughput

0.489

High

502565

H2A1
Histone H2A type 1

1

1

High-throughput

0.489

High

518919

CCL3
C-C motif chemokine 3

1

2

High-throughput

0.489

High

1252691

ZN574
Zinc finger protein 574

1

1

High-throughput

0.489

High

1385370

DHX58
ATP-dependent RNA helicase DHX58

1

5

High-throughput

0.489

High

1397751

MAGBA
Melanoma-associated antigen B10

1

2

High-throughput

0.489

High

1452150

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

3

High-throughput

0.489

High

173460

XPO1
Exportin-1

1

2

High-throughput

0.479

High

194370

R113A
E3 ubiquitin-protein ligase RNF113A

1

1

High-throughput

0.479

High

243127

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

260541

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

373317

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

406726

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

414729

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

487821

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

607162

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

799521

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

810426

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

851684

GATA4
Transcription factor GATA-4

1

1

High-throughput

0.479

High

879537

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

965281

WDR5
WD repeat-containing protein 5

1

2

High-throughput

0.479

High

1094484

IFT88
Intraflagellar transport protein 88 homolog

1

2

High-throughput

0.479

High

1129766

MDC1
Mediator of DNA damage checkpoint protein 1

1

3

High-throughput

0.479

High

1152656

ELAV1
ELAV-like protein 1

1

1

High-throughput

0.479

High

1289663

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1313475

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1339002

NUP43
Nucleoporin Nup43

1

5

High-throughput

0.479

High

1367428

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1369859

CELF1
CUGBP Elav-like family member 1

1

3

High-throughput

0.479

High

1387597

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

4

High-throughput

0.479

High

1406789

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.479

High

1407915

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1452148

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

238625

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

377752

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

461983

HS90A
Heat shock protein HSP 90-alpha

1

0

High-throughput

0.458

High

558446

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

846502

MATR3
Matrin-3

1

0

High-throughput

0.458

High

935197

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1029957

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

1143562

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1368153

HDAC2
Histone deacetylase 2

1

0

High-throughput

0.458

High

1432562

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.458

High

1445980

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.458

High

290765

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.445

High

785491

RL4
Large ribosomal subunit protein uL4

1

1

High-throughput

0.445

High

1006753

SRPK2
SRSF protein kinase 2

1

3

High-throughput

0.445

High

1008912

RED1
Double-stranded RNA-specific editase 1

1

4

High-throughput

0.445

High

1037415

H11
Histone H1.1

1

4

High-throughput

0.445

High

1244337

PSRC1
Proline/serine-rich coiled-coil protein 1

1

1

High-throughput

0.445

High

1451801

LYAR
Cell growth-regulating nucleolar protein

1

1

High-throughput

0.445

High

341690

EYA4
Protein phosphatase EYA4

1

1

High-throughput

0.437

High

376017

RASK
GTPase KRas

1

3

High-throughput

0.437

High

1140943

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

1255825

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

1276875

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1434061

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1452149

XPO7
Exportin-7

1

2

High-throughput

0.437

High

208402

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.426

High

584153

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.426

High

1057002

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.426

High

1239963

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1335003

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.426

High

1452147

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.426

High

1452154

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.426

High

887268

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

104299

F5H6C2
Intraflagellar transport 88

1

1

High-throughput

0.407

High

1395547

S45A3
Solute carrier family 45 member 3

1

2

High-throughput

0.407

High

1446078

S39A2
Zinc transporter ZIP2

1

1

High-throughput

0.407

High

465983

CO1A2
Collagen alpha-2(I) chain

1

0

High-throughput

0.279

Low

522745

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.279

Low

535599

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.279

Low

547005

FGF3
Fibroblast growth factor 3

1

0

High-throughput

0.279

Low

608367

EGLN
Endoglin

1

0

High-throughput

0.279

Low

866450

CASA1
Alpha-S1-casein [Cleaved into: Casoxin-D]

1

0

High-throughput

0.279

Low

889021

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.279

Low

902899

BLK
Tyrosine-protein kinase Blk

1

0

High-throughput

0.279

Low

933489

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.279

Low

948480

ARPC4
Actin-related protein 2/3 complex subunit 4

1

0

High-throughput

0.279

Low

1357266

CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2

1

0

High-throughput

0.279

Low

1388433

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.279

Low

1397714

ZSC31
Zinc finger and SCAN domain-containing protein 31

1

0

High-throughput

0.279

Low

1452156

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.279

Low

869998

ATPO
ATP synthase peripheral stalk subunit OSCP, mitochondrial

1

0

High-throughput

0.269

Low

1218364

OTUD1
OTU domain-containing protein 1

1

0

High-throughput

0.249

Low

1258396

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.249

Low

1338403

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1358120

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

1386392

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

1155104

UT2
Urea transporter 2

1

0

High-throughput

0.232

Low

1406751

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

1

0

High-throughput

0.232

Low

1428264

S6A16
Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025