HitPredict

Interactor 1: ARNT (O15945)
Aryl hydrocarbon receptor nuclear translocator homolog (dARNT) (Hypoxia-inducible factor 1-beta) (Protein tango)
Gene: tgo

Interactor 2: Q9V490 (Q9V490)
GH14454p (Twin of eyeless, isoform A)
Gene: toy

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	30995488
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 642 Dm			1 543
+	Dm
		111955 ARNT_DROME (1-642): 0: 569: 100.00		L0MPR7_DROME (1-543): 5.17e-123: 373: 96.87
+	Hs
		620128 ARNT_HUMAN (2-641): 2.26e-164: 491: 39.58		PAX7_HUMAN (4-499): 9.73e-63: 215: 24.21
+	Hs
		641405 SIM2_HUMAN (14-641): 6.06e-130: 399: 18.83		PAX6_HUMAN (29-543): 4.12e-76: 248: 45.75
+	Hs
		641617 NCOA3_HUMAN (1-609): 7.98e-101: 337: 18.10		PAX6_HUMAN (29-543): 4.12e-76: 248: 45.75
+	Hs
		620231 NCOA3_HUMAN (1-609): 7.98e-101: 337: 18.10		PAX7_HUMAN (4-499): 9.73e-63: 215: 24.21
+	Hs
		973898 NCOA3_HUMAN (1-609): 7.98e-101: 337: 18.10		PAX2_HUMAN (23-453): 5.81e-61: 208: 32.10
+	Hs
		988822 NCOA3_HUMAN (1-609): 7.98e-101: 337: 18.10		PAX8_HUMAN (25-501): 4.2e-57: 199: 27.63
+	Hs
		988765 NCOA2_HUMAN (2-610): 5.34e-98: 330: 17.82		PAX8_HUMAN (25-501): 4.2e-57: 199: 27.63
+	Hs
		878484 NCOA3_HUMAN (1-609): 7.98e-101: 337: 18.10		PAX9_HUMAN (31-262): 1.64e-43: 159: 42.31
+	Hs
		878410 NCOA2_HUMAN (2-610): 5.34e-98: 330: 17.82		PAX9_HUMAN (31-262): 1.64e-43: 159: 42.31