HitPredict

Interactor 1: O16453 (O16453)
Ferritin (EC 1.16.3.1)
Gene: ftn-1

Interactor 2: Q9TYS3 (Q9TYS3)
Ferritin (EC 1.16.3.1)
Gene: ftn-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.826

Property	Details
Experiments	19123269, 14704431
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ferritin~Ferritin
Common GO terms	GO:0004322 - ferroxidase activity GO:0005737 - cytoplasm GO:0006826 - iron ion transport GO:0006880 - intracellular sequestering of iron ion GO:0008198 - ferrous iron binding and 1 others more... GO:0008199 - ferric iron binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 170 Ce			1 170
+	Hs
		365121 FRIH_HUMAN (2-170): 7.18e-75: 223: 54.07		FRIH_HUMAN (2-170): 4.17e-75: 224: 60.47
+	At
		1107009 FRI1_ARATH (2-169): 2.32e-73: 222: 44.77		FRI1_ARATH (2-169): 1.56e-73: 222: 47.67
+	Hs
		1157509 Q6NZ44_HUMAN (2-170): 1.79e-73: 220: 52.91		Q6NZ44_HUMAN (2-170): 1.07e-73: 220: 59.30
+	Mm
		451809 FRIH_MOUSE (2-169): 6.11e-73: 218: 53.80		FRIH_MOUSE (2-169): 3.83e-73: 219: 60.82
+	At
		1107014 FRI1_ARATH (2-169): 2.32e-73: 222: 44.77		FRI3_ARATH (1-169): 7.35e-70: 213: 52.60
+	Ce
		1353436 Q9TYS3_CAEEL (1-170): 2.45e-72: 216: 78.82		Q9TYS3_CAEEL (1-170): 1.5e-72: 217: 100.00
+	Hs
		364816 FRIH_HUMAN (2-170): 7.18e-75: 223: 54.07		FRIL_HUMAN (2-168): 9.39e-68: 205: 49.41
+	Hs
		364926 Q6NZ44_HUMAN (2-170): 1.79e-73: 220: 52.91		FRIL_HUMAN (2-168): 9.39e-68: 205: 49.41
+	Mm
		451814 FRIH_MOUSE (2-169): 6.11e-73: 218: 53.80		Q9CPX4_MOUSE (2-168): 4.26e-68: 206: 47.75
+	Ce
		183894 O16453_CAEEL (1-170): 7.76e-70: 210: 100.00		O16453_CAEEL (1-170): 1.12e-69: 210: 78.82
+	Mm
		1321681 Q9CPX4_MOUSE (2-168): 5.4e-68: 206: 42.70		Q9CPX4_MOUSE (2-168): 4.26e-68: 206: 47.75
+	Hs
		364815 FRIL_HUMAN (2-168): 1.22e-67: 205: 43.53		FRIL_HUMAN (2-168): 9.39e-68: 205: 49.41
+	Dm
		1375733 Q9VYH1_DROME (3-167): 9.13e-65: 198: 37.58		Q9VYH1_DROME (3-167): 1.22e-64: 197: 40.00
+	Af
		191424 O29424_ARCFU (9-169): 1.87e-50: 161: 30.44		O29424_ARCFU (9-167): 3.9e-50: 160: 31.25
+	Dm
		1181662 FRIH_DROME (10-167): 1.12e-50: 163: 34.13		FRIL_DROME (10-167): 2.71e-41: 139: 22.54
+	Dm
		82238 B8A405_DROME (10-167): 4.42e-47: 155: 34.13		FRIL_DROME (10-167): 2.71e-41: 139: 22.54