Interactor 1: ORC1 (O16810)
Origin recognition complex subunit 1 (DmORC1)
Gene: ORC1

Interactor 2: Q9VSM9 (Q9VSM9)
Cell division control protein
Gene: Cdc6

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 29899147, 32848132
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA_22, AAA~Cdc6_C, AAA_lid_10~Cdc6_C, Cdc6_C~Cdc6_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0006270 - DNA replication initiation
GO:0016887 - ATP hydrolysis activity
GO:0033314 - mitotic DNA replication checkpoint signaling
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 924
Dm

1 662
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp
+ Sp
+ Sp
+ Sc
+ Sp
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024