HitPredict

Interactor 1: RAN (O17915)
GTP-binding nuclear protein ran-1 (Ras-related nuclear protein 1)
Gene: ran-1

Interactor 2: Q9UAQ6 (Q9UAQ6)
RAB family
Gene: rab-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	14704431
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 215 Ce			1 205
+	Mm
		895595 RAB35_MOUSE (5-176): 1.19e-86: 256: 29.89		RAB8B_MOUSE (4-199): 3.25e-96: 280: 56.50
+	Hs
		918874 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RAB1A_HUMAN (1-205): 1.4e-91: 268: 79.51
+	Mm
		918986 RAB35_MOUSE (5-176): 1.19e-86: 256: 29.89		RAB1A_MOUSE (1-205): 1.4e-91: 268: 79.51
+	Mm
		1161509 RAB35_MOUSE (5-176): 1.19e-86: 256: 29.89		RAB1B_MOUSE (4-205): 1.65e-86: 255: 78.22
+	Mm
		877193 RAB35_MOUSE (5-176): 1.19e-86: 256: 29.89		RAB8A_MOUSE (4-203): 6.34e-86: 253: 53.50
+	Sc
		350828 YPT1_YEAST (4-176): 3.43e-85: 252: 27.27		YPT1_YEAST (4-205): 4.37e-86: 254: 66.99
+	Hs
		918846 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAB1A_HUMAN (1-205): 1.4e-91: 268: 79.51
+	Zm
		73944 B4FAE1_MAIZE (4-205): 6.63e-83: 246: 26.83		B4FAE1_MAIZE (4-205): 8.13e-88: 258: 74.26
+	Hs
		918944 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAB1B_HUMAN (4-205): 1.54e-86: 255: 78.22
+	Mm
		919000 RAB1A_MOUSE (1-196): 9.74e-80: 238: 26.87		RAB1B_MOUSE (4-205): 1.65e-86: 255: 78.22
+	Hs
		913992 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RB11A_HUMAN (1-205): 3.57e-84: 250: 48.36
+	Hs
		913989 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RB11A_HUMAN (1-205): 3.57e-84: 250: 48.36
+	Hs
		918879 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RB11B_HUMAN (1-205): 5.88e-83: 247: 46.98
+	Hs
		896605 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAB14_HUMAN (1-205): 6.55e-83: 246: 41.86
+	Hs
		894715 RAB1A_HUMAN (1-196): 9.74e-80: 238: 26.87		RAB8A_HUMAN (4-203): 4.83e-82: 244: 53.00
+	Hs
		914093 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RB11B_HUMAN (1-205): 5.88e-83: 247: 46.98
+	Hs
		845854 RAB35_HUMAN (5-176): 1.19e-86: 256: 29.89		RAB13_HUMAN (4-184): 1.81e-74: 224: 57.46
+	Hs
		894712 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RAB8A_HUMAN (4-203): 4.83e-82: 244: 53.00
+	Hs
		845845 RB11A_HUMAN (3-204): 3.8e-78: 235: 24.76		RAB13_HUMAN (4-184): 1.81e-74: 224: 57.46