HitPredict

Interactor 1: PITX (O18400)
Pituitary homeobox homolog Ptx1 (D-PTX1)
Gene: Ptx1

Interactor 2: DRM (Q9VQS6)
Protein drumstick
Gene: DRM

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	30995488
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 509 Dm			1 81
+	Hs
		575278 PAX6_HUMAN (212-496): 7.45e-42: 156: 23.86		EGR1_HUMAN (2-81): 1.96e-22: 90.9: 21.18
+	Hs
		563558 PAX7_HUMAN (247-505): 3.14e-33: 134: 25.83		ZNF24_HUMAN (24-81): 2.72e-27: 102: 32.76
+	Dm
		1185983 Q7PL95_DROME (68-450): 1.23e-31: 129: 16.75		DRM_DROME (1-81): 3.06e-31: 105: 100.00
+	Dm
		65369 A8DYR8_DROME (77-473): 6.13e-29: 120: 21.13		DRM_DROME (1-81): 3.06e-31: 105: 100.00
+	Dm
		1359812 Q9V490_DROME (208-498): 5.6e-31: 127: 21.98		SOB_DROME (20-74): 3.7e-22: 90.2: 60.00
+	Dm
		111997 L0MPR7_DROME (208-498): 3.26e-30: 125: 23.26		SOB_DROME (20-74): 3.7e-22: 90.2: 60.00
+	Mm
		434886 PITX1_MOUSE (202-500): 2.3e-31: 125: 33.78		EGR1_MOUSE (2-81): 2.89e-22: 90.1: 21.18
+	Hs
		201852 HXA2_HUMAN (113-479): 1.29e-30: 124: 14.44		EGR1_HUMAN (2-81): 1.96e-22: 90.9: 21.18
+	Hs
		575368 PITX1_HUMAN (211-500): 3.07e-30: 122: 34.48		EGR1_HUMAN (2-81): 1.96e-22: 90.9: 21.18
+	Hs
		641511 PAX6_HUMAN (212-496): 7.45e-42: 156: 23.86		ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03
+	Hs
		641448 PAX6_HUMAN (212-496): 7.45e-42: 156: 23.86		ZN746_HUMAN (28-73): 1.68e-09: 54: 36.96
+	Hs
		641575 PAX6_HUMAN (212-496): 7.45e-42: 156: 23.86		SALL1_HUMAN (4-73): 3.46e-09: 53.2: 30.00
+	Mm
		1206624 Q8VD35_MOUSE (256-480): 3.65e-38: 143: 26.58		ZN787_MOUSE (55-81): 2.65e-09: 53.2: 33.33
+	Dm
		1372733 Q9XZU0_DROME (262-324): 5.74e-17: 84.3: 61.91		DRM_DROME (1-81): 3.06e-31: 105: 100.00
+	Hs
		620188 PAX7_HUMAN (247-505): 3.14e-33: 134: 25.83		ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03
+	Hs
		620163 PAX7_HUMAN (247-505): 3.14e-33: 134: 25.83		ZN746_HUMAN (28-73): 1.68e-09: 54: 36.96
+	Hs
		1077276 ALX1_HUMAN (237-474): 1.25e-31: 126: 23.95		ZN300_HUMAN (4-81): 2.37e-10: 56.3: 14.82
+	Hs
		822658 LHX1_HUMAN (205-497): 3.74e-30: 123: 17.69		ZKSC4_HUMAN (51-81): 1e-09: 54.8: 29.03
+	Hs
		882163 GSC_HUMAN (120-355): 1.71e-28: 115: 21.61		SALL1_HUMAN (4-73): 3.46e-09: 53.2: 30.00
+	Hs
		156120 PHX2A_HUMAN (254-324): 1.53e-18: 87.8: 59.16		SP1_HUMAN (2-49): 3.77e-17: 75.8: 25.00