HitPredict

Interactor 1: HDA19 (O22446)
Histone deacetylase 19 (AtHD1) (HD) (EC 3.5.1.98)
Gene: HDA19

Interactor 2: SNL3 (O48686)
Paired amphipathic helix protein Sin3-like 3 (Histone deacetylase complex subunit Sin3) (AtSin3) (Transcriptional corepressor Sin3)
Gene: SNL3

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15994908
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 At			1 1330
+	At
		186887 HDA19_ARATH (1-501): 0: 671: 100.00		SNL1_ARATH (3-1327): 0: 1243: 45.07
+	Mm
		140278 HDAC1_MOUSE (12-451): 0: 629: 61.77		SIN3B_MOUSE (594-1328): 8.7e-142: 462: 15.10
+	Hs
		257815 HDAC2_HUMAN (8-494): 0: 634: 56.03		SIN3B_HUMAN (613-1328): 9.56e-128: 425: 13.47
+	Hs
		257779 HDAC1_HUMAN (12-451): 0: 626: 61.31		SIN3B_HUMAN (613-1328): 9.56e-128: 425: 13.47
+	Hs
		1270395 HDAC2_HUMAN (8-494): 0: 634: 56.03		SIN3A_HUMAN (663-1326): 1.88e-106: 368: 14.42
+	Mm
		936394 HDAC2_MOUSE (8-494): 0: 632: 56.24		SIN3A_MOUSE (663-1326): 1.85e-105: 365: 14.55
+	Hs
		1038650 HDAC1_HUMAN (12-451): 0: 626: 61.31		SIN3A_HUMAN (663-1326): 1.88e-106: 368: 14.42
+	Mm
		140270 HDAC1_MOUSE (12-451): 0: 629: 61.77		SIN3A_MOUSE (663-1326): 1.85e-105: 365: 14.55
+	Mm
		1143586 HDAC4_MOUSE (7-420): 4.02e-132: 410: 22.00		SIN3B_MOUSE (594-1328): 8.7e-142: 462: 15.10
+	Mm
		140313 HDAC1_MOUSE (12-451): 0: 629: 61.77		GON4L_MOUSE (15-286): 1.52e-53: 209: 18.82
+	Sp
		140530 PHD1_SCHPO (14-420): 0: 530: 53.66		PST3_SCHPO (1051-1328): 2.49e-68: 254: 14.63
+	Hs
		880810 HDAC4_HUMAN (7-420): 7.05e-130: 405: 20.63		SIN3A_HUMAN (663-1326): 1.88e-106: 368: 14.42
+	Dm
		1137165 HDAC1_DROME (12-495): 0: 610: 54.43		Q5U0Y0_DROME (88-183): 1.1e-20: 101: 36.70
+	Dm
		184384 HDAC1_DROME (12-495): 0: 610: 54.43		O17142_DROME (88-183): 9.41e-21: 101: 36.70
+	Ce
		60834 HDA1_CAEEL (1-455): 0: 584: 55.87		SIN3_CAEEL (3-96): 2.89e-24: 113: 41.00
+	Ce
		60810 G5ECH0_CAEEL (13-451): 0: 563: 54.71		SIN3_CAEEL (3-96): 2.89e-24: 113: 41.00
+	Sc
		609058 RPD3_YEAST (16-433): 0: 577: 54.31		SIN3_YEAST (95-349): 5.64e-19: 95.8: 16.42
+	Sp
		140653 PHD1_SCHPO (14-420): 0: 530: 53.66		PST1_SCHPO (2-76): 2.81e-09: 64.2: 25.33
+	Sc
		609122 HDA1_YEAST (18-338): 3.67e-116: 359: 24.06		SIN3_YEAST (95-349): 5.64e-19: 95.8: 16.42
+	Dm
		1137160 Q86NK9_DROME (15-333): 6.46e-88: 293: 22.36		Q5U0Y0_DROME (88-183): 1.1e-20: 101: 36.70