HitPredict

Interactor 1: PHB2 (O35129)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity)
Gene: PHB2

Interactor 2: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0030424 - axon
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 299 Mm			1 733
+	Rn
		582006 PHB2_RAT (1-299): 1.04e-109: 321: 99.67		TAU_RAT (1-733): 1.67e-78: 268: 88.46
+	Rn
		94230 PHB2_RAT (1-299): 1.04e-109: 321: 99.67		F1LST4_RAT (1-732): 4.29e-78: 268: 88.58
+	Mm
		498000 PHB1_MOUSE (22-280): 6.64e-86: 260: 51.54		TAU_MOUSE (1-733): 4.79e-86: 288: 100.00
+	Hs
		497489 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496431 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		496354 STOM_HUMAN (1-286): 2.42e-84: 256: 17.93		TAU_HUMAN (1-733): 3.71e-62: 224: 69.50
+	Hs
		1056952 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		MDC1_HUMAN (2-721): 9.17e-27: 119: 9.02
+	Hs
		653924 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49