Protein: CSN7A
COP9 signalosome complex subunit 7a (SGN7a) (Signalosome subunit 7a) (Dermal papilla-derived protein 10) (JAB1-containing signalosome subunit 7a)

Gene: CSN7A, COPS7A
Organism: Homo sapiens
Interactions: 139
UniProt ID: Q9UBW8

Gene Ontology (top 5):
GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1272670

CSN5
COP9 signalosome complex subunit 5

17

20

Small-scale

0.986

High

1185003

CSN6
COP9 signalosome complex subunit 6

13

20

Small-scale

0.982

High

1354429

CSN3
COP9 signalosome complex subunit 3

13

18

Small-scale

0.980

High

1305357

CSN8
COP9 signalosome complex subunit 8

10

3

Small-scale

0.972

High

897324

CSN2
COP9 signalosome complex subunit 2

8

20

Small-scale

0.968

High

1311913

CSN4
COP9 signalosome complex subunit 4

6

9

Small-scale

0.947

High

1024236

CSN1
COP9 signalosome complex subunit 1

4

20

Small-scale

0.895

High

1334406

CSN7B
COP9 signalosome complex subunit 7b

2

2

High-throughput

0.811

High

1042750

CUL3
Cullin-3

9

12

Small-scale

0.751

High

1265910

DDB2
DNA damage-binding protein 2

7

4

Small-scale

0.746

High

1043276

CUL4A
Cullin-4A

7

12

Small-scale

0.743

High

1043630

CUL4B
Cullin-4B

5

12

Small-scale

0.718

High

1255960

DCA11
DDB1- and CUL4-associated factor 11

5

2

High-throughput

0.718

High

1041247

CUL1
Cullin-1

5

12

Small-scale

0.712

High

1082441

DDB1
DNA damage-binding protein 1

4

1

Small-scale

0.686

High

1028034

ERCC8
DNA excision repair protein ERCC-8

4

3

Small-scale

0.676

High

1327497

BTBD1
BTB/POZ domain-containing protein 1

3

7

High-throughput

0.675

High

896249

UBC12
NEDD8-conjugating enzyme Ubc12

3

2

High-throughput

0.667

High

1041487

CUL2
Cullin-2

3

12

High-throughput

0.667

High

1185099

DET1
DET1 homolog

3

1

High-throughput

0.667

High

1260943

DCAF4
DDB1- and CUL4-associated factor 4

3

2

High-throughput

0.667

High

1274073

CUL5
Cullin-5

3

12

High-throughput

0.667

High

1354433

DCAF1
DDB1- and CUL4-associated factor 1

3

4

Small-scale

0.656

High

1081257

NF2L2
Nuclear factor erythroid 2-related factor 2

2

6

Small-scale

0.629

High

319420

APBB3
Amyloid-beta A4 precursor protein-binding family B member 3

2

1

High-throughput

0.628

High

469827

RB40L
Ras-related protein Rab-40A-like

2

2

High-throughput

0.628

High

1031294

SKP2
S-phase kinase-associated protein 2

2

1

High-throughput

0.628

High

1153797

KLH10
Kelch-like protein 10

2

3

High-throughput

0.628

High

1315084

BTBD2
BTB/POZ domain-containing protein 2

2

7

High-throughput

0.628

High

1354432

FBX7
F-box only protein 7

2

1

High-throughput

0.628

High

921459

RBX1
E3 ubiquitin-protein ligase RBX1

2

2

High-throughput

0.611

High

1079621

NEDD8
NEDD8

2

3

Small-scale

0.611

High

1296809

LLR1
Leucine-rich repeat protein 1

2

1

High-throughput

0.611

High

1314412

DDA1
DET1- and DDB1-associated protein 1

2

1

High-throughput

0.611

High

297687

RHBT1
Rho-related BTB domain-containing protein 1

3

3

High-throughput

0.609

High

1230767

FXL14
F-box/LRR-repeat protein 14

2

0

High-throughput

0.602

High

1354434

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

3

Small-scale

0.584

High

934539

CSK21
Casein kinase II subunit alpha

1

4

Small-scale

0.578

High

91400

E7EM64
COP9 signalosome complex subunit 6

1

20

High-throughput

0.575

High

92483

E9PGT6
COP9 signalosome subunit 8

1

3

High-throughput

0.575

High

207749

DENR
Density-regulated protein

2

1

High-throughput

0.574

High

1068515

KPCD1
Serine/threonine-protein kinase D1

1

3

Small-scale

0.561

High

158558

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

Small-scale

0.552

High

722987

PGH2
Prostaglandin G/H synthase 2

1

0

Small-scale

0.537

High

50465

SYCE3
Synaptonemal complex central element protein 3

1

1

High-throughput

0.536

High

279048

RAD17
Cell cycle checkpoint protein RAD17

1

1

High-throughput

0.536

High

566797

JUNB
Transcription factor JunB

1

5

High-throughput

0.536

High

588959

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

1

High-throughput

0.536

High

828926

SRP09
Signal recognition particle 9 kDa protein

1

1

High-throughput

0.536

High

1075469

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

2

High-throughput

0.536

High

1079175

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.536

High

1129916

DCA10
DDB1- and CUL4-associated factor 10

1

1

High-throughput

0.536

High

1191317

KCD20
BTB/POZ domain-containing protein KCTD20

1

2

High-throughput

0.536

High

1241272

FA98A
Protein FAM98A

1

1

High-throughput

0.536

High

1263350

CSN9
COP9 signalosome complex subunit 9

1

1

High-throughput

0.536

High

1289622

FBX17
F-box only protein 17

1

3

High-throughput

0.536

High

1292401

DCNL1
DCN1-like protein 1

1

1

High-throughput

0.536

High

1299040

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

1

High-throughput

0.536

High

1309909

COR1B
Coronin-1B

1

2

High-throughput

0.536

High

1317807

NUF2
Kinetochore protein Nuf2

1

1

High-throughput

0.536

High

1346172

AP5S1
AP-5 complex subunit sigma-1

1

1

High-throughput

0.536

High

1347548

ASB6
Ankyrin repeat and SOCS box protein 6

1

1

High-throughput

0.536

High

1350480

KLH13
Kelch-like protein 13

1

3

High-throughput

0.536

High

1354435

SAR1B
Small COPII coat GTPase SAR1B

1

2

High-throughput

0.536

High

1159461

FBX42
F-box only protein 42

2

3

High-throughput

0.533

High

272825

TM1L1
TOM1-like protein 1

1

0

High-throughput

0.518

High

179069

TNC18
Trinucleotide repeat-containing gene 18 protein

1

0

High-throughput

0.513

High

241913

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.513

High

679407

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

1

0

High-throughput

0.513

High

1128043

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.513

High

1233822

CCD82
Coiled-coil domain-containing protein 82

1

0

High-throughput

0.513

High

1283501

ISL2
Insulin gene enhancer protein ISL-2

1

0

High-throughput

0.513

High

1290773

MCRS1
Microspherule protein 1

1

0

High-throughput

0.513

High

1347540

PLAT2
Phospholipase A and acyltransferase 2

1

0

High-throughput

0.513

High

1354425

CDC23
Cell division cycle protein 23 homolog

1

0

High-throughput

0.513

High

1354427

FBXL5
F-box/LRR-repeat protein 5

1

0

High-throughput

0.513

High

1121810

ANR39
Ankyrin repeat domain-containing protein 39

1

2

High-throughput

0.489

High

1238364

SYT2
Synaptotagmin-2

1

1

High-throughput

0.489

High

375036

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

Small-scale

0.481

High

1191247

CPEB2
Cytoplasmic polyadenylation element-binding protein 2

1

1

Small-scale

0.481

High

931919

CSK2B
Casein kinase II subunit beta

1

0

Small-scale

0.480

High

295357

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

553967

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

652508

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

714596

GRK5
G protein-coupled receptor kinase 5

1

1

High-throughput

0.479

High

721685

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

818561

SOX2
Transcription factor SOX-2

1

1

Small-scale

0.479

High

875398

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

885062

FBXW4
F-box/WD repeat-containing protein 4

1

5

Small-scale

0.479

High

915108

RS4X
Small ribosomal subunit protein eS4, X isoform

1

1

High-throughput

0.479

High

992498

SOS1
Son of sevenless homolog 1

1

2

Small-scale

0.479

High

1072475

ELOB
Elongin-B

1

1

High-throughput

0.479

High

1077153

MARE1
Microtubule-associated protein RP/EB family member 1

1

1

Small-scale

0.479

High

1123681

DCAF6
DDB1- and CUL4-associated factor 6

1

7

High-throughput

0.479

High

1148845

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1172116

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1234394

WDTC1
WD and tetratricopeptide repeats protein 1

1

6

High-throughput

0.479

High

1243979

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1246191

COP1
E3 ubiquitin-protein ligase COP1

1

3

High-throughput

0.479

High

1262832

PHIP
PH-interacting protein

1

2

Small-scale

0.479

High

1270722

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.479

High

1302568

CRBN
Protein cereblon

1

1

Small-scale

0.479

High

1311122

BTBDA
BTB/POZ domain-containing protein 10

1

2

High-throughput

0.479

High

1319020

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

2

High-throughput

0.479

High

1331534

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1342376

RAB18
Ras-related protein Rab-18

1

1

Small-scale

0.479

High

1344591

FBX6
F-box only protein 6

1

3

High-throughput

0.479

High

1349192

DTL
Denticleless protein homolog

1

2

High-throughput

0.479

High

1354424

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1354428

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.479

High

1354430

NOD1
Nucleotide-binding oligomerization domain-containing protein 1

1

1

Small-scale

0.479

High

1354431

FBW1A
F-box/WD repeat-containing protein 1A

1

3

Small-scale

0.479

High

1158409

PMF1
Polyamine-modulated factor 1

1

0

Small-scale

0.460

High

727198

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

1039474

IRF5
Interferon regulatory factor 5

1

0

Small-scale

0.458

High

1347960

DCA16
DDB1- and CUL4-associated factor 16

1

0

High-throughput

0.458

High

1354426

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

81623

B7Z503
BTB

1

2

High-throughput

0.445

High

99491

F5GZ90
Denticleless E3 ubiquitin protein ligase homolog

1

4

High-throughput

0.445

High

402574

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

497730

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

968664

TAGL
Transgelin

1

2

High-throughput

0.445

High

1120824

KLH12
Kelch-like protein 12

1

3

High-throughput

0.445

High

500909

CLUS
Clusterin

1

0

High-throughput

0.438

High

1344796

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

975088

CAV1
Caveolin-1

1

1

Small-scale

0.437

High

1126396

CT451
Cancer/testis antigen family 45 member A1

1

3

High-throughput

0.437

High

1317633

RHBT2
Rho-related BTB domain-containing protein 2

1

4

High-throughput

0.437

High

1063130

ABRX2
BRISC complex subunit Abraxas 2

1

0

Small-scale

0.426

High

483730

CT456
Cancer/testis antigen family 45 member A6

1

3

High-throughput

0.407

High

1245972

CT453
Cancer/testis antigen family 45 member A3

1

3

High-throughput

0.407

High

428819

CASK
Kappa-casein

2

0

Small-scale

0.305

High

364064

CXCL7
Platelet basic protein

1

0

High-throughput

0.282

High

1139565

SLX4I
Protein SLX4IP

1

0

High-throughput

0.279

Low

1302878

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.279

Low

409388

CASB
Beta-casein

1

0

Small-scale

0.249

Low

812808

CASA1
Alpha-S1-casein [Cleaved into: Casoxin-D]

1

0

Small-scale

0.249

Low

1256543

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.249

Low

1330711

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024