HitPredict

Interactor 1: ALX4 (O35137)
Homeobox protein aristaless-like 4 (ALX-4)
Gene: ALX4

Interactor 2: LDB1 (P70662)
LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (mLdb1) (Nuclear LIM interactor)
Gene: LDB1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20211142
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001942 - hair follicle development GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 399 Mm			1 411
+	Hs
		620170 PAX7_HUMAN (179-374): 1.07e-41: 155: 29.25		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Hs
		641465 PAX6_HUMAN (123-379): 1.66e-32: 128: 24.81		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Mm
		936872 PITX2_MOUSE (156-393): 2.72e-32: 125: 26.95		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Mm
		925846 LHX1_MOUSE (144-379): 6.46e-30: 121: 21.55		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Mm
		936889 LMX1A_MOUSE (166-379): 4.04e-30: 121: 17.29		LDB1_MOUSE (1-411): 0: 760: 100.00
+	Hs
		822644 LHX1_HUMAN (144-379): 1.04e-29: 120: 21.55		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Hs
		238112 LMX1B_HUMAN (160-339): 5.08e-29: 118: 23.89		LDB1_HUMAN (1-411): 0: 760: 99.76
+	Mm
		223249 LHX1_MOUSE (144-379): 6.46e-30: 121: 21.55		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Mm
		223259 LMX1A_MOUSE (166-379): 4.04e-30: 121: 17.29		LDB2_MOUSE (44-411): 0: 626: 76.15
+	Dm
		112541 M9NCY1_DROME (150-394): 2.95e-29: 119: 18.78		Q7KVG9_DROME (8-391): 0: 593: 56.89
+	Ce
		106912 HM14_CAEEL (194-367): 1.31e-29: 119: 21.91		LIDB1_CAEEL (33-408): 2.59e-137: 407: 27.85