Protein: YKT6
Synaptobrevin homolog YKT6 (EC 2.3.1.-)

Gene: YKT6
Organism: Homo sapiens
Interactions: 215
UniProt ID: O15498

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005484 - SNAP receptor activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

189323

STX7
Syntaxin-7

5

20

Small-scale

0.922

High

192221

PGTB2
Geranylgeranyl transferase type-2 subunit beta

4

2

High-throughput

0.892

High

192248

STX3
Syntaxin-3

4

20

High-throughput

0.892

High

192275

STX12
Syntaxin-12

4

20

High-throughput

0.892

High

192213

FNTB
Protein farnesyltransferase subunit beta

3

2

High-throughput

0.861

High

192247

STX5
Syntaxin-5

3

20

Small-scale

0.861

High

192149

STX11
Syntaxin-11

2

20

High-throughput

0.811

High

192222

SNAA
Alpha-soluble NSF attachment protein

2

19

High-throughput

0.811

High

192145

STX6
Syntaxin-6

2

20

High-throughput

0.789

High

192155

VAMP5
Vesicle-associated membrane protein 5

1

15

High-throughput

0.691

High

192286

SCFD1
Sec1 family domain-containing protein 1

1

15

High-throughput

0.691

High

192305

SNAG
Gamma-soluble NSF attachment protein

1

19

High-throughput

0.691

High

192343

STX8
Syntaxin-8

1

20

High-throughput

0.691

High

192271

PTAR1
Protein prenyltransferase alpha subunit repeat-containing protein 1

3

2

High-throughput

0.662

High

179756

BET1
BET1 homolog

3

20

High-throughput

0.657

High

192163

RASK
GTPase KRas

3

18

High-throughput

0.640

High

192164

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

7

High-throughput

0.640

High

192227

T2R41
Taste receptor type 2 member 41

3

0

High-throughput

0.638

High

192339

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

3

0

High-throughput

0.638

High

192288

PGTA
Geranylgeranyl transferase type-2 subunit alpha

2

2

High-throughput

0.628

High

192308

AASD1
Alanyl-tRNA editing protein Aarsd1

2

1

High-throughput

0.628

High

192156

GOSR1
Golgi SNAP receptor complex member 1

1

10

Small-scale

0.618

High

192152

C1QRF
C1q-related factor

2

0

High-throughput

0.602

High

192337

ANFY1
Rabankyrin-5

1

0

High-throughput

0.586

High

192161

RASN
GTPase NRas

2

18

High-throughput

0.584

High

192177

LAMP1
Lysosome-associated membrane glycoprotein 1

2

8

High-throughput

0.584

High

192235

ARF6
ADP-ribosylation factor 6

2

4

High-throughput

0.584

High

192236

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.584

High

192237

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

192330

BET1L
BET1-like protein

2

18

Small-scale

0.584

High

192175

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.554

High

192158

SNP29
Synaptosomal-associated protein 29

1

20

High-throughput

0.536

High

192212

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

2

High-throughput

0.536

High

192246

ARL16
ADP-ribosylation factor-like protein 16

1

20

High-throughput

0.536

High

192332

USE1
Vesicle transport protein USE1

1

5

High-throughput

0.536

High

192210

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

High-throughput

0.513

High

192219

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

192259

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.513

High

192277

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

192324

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

192187

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

High-throughput

0.493

High

192204

HSPA9
Stress-70 protein, mitochondrial

1

2

High-throughput

0.481

High

48445

ESYT2
Extended synaptotagmin-2

1

4

High-throughput

0.479

High

124152

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.479

High

126377

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

139769

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.479

High

154448

CLD4
Claudin-4

1

1

Small-scale

0.479

High

173779

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

4

High-throughput

0.479

High

192144

TGON2
Trans-Golgi network integral membrane protein 2

1

4

High-throughput

0.479

High

192146

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.479

High

192148

MTX2
Metaxin-2

1

2

High-throughput

0.479

High

192150

NU155
Nuclear pore complex protein Nup155

1

1

High-throughput

0.479

High

192151

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

192157

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.479

High

192162

RASH
GTPase HRas

1

12

High-throughput

0.479

High

192165

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

192166

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.479

High

192167

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

192168

INSR
Insulin receptor

1

11

High-throughput

0.479

High

192170

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

8

High-throughput

0.479

High

192171

IGF1R
Insulin-like growth factor 1 receptor

1

13

High-throughput

0.479

High

192172

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

192178

FGFR1
Fibroblast growth factor receptor 1

1

9

High-throughput

0.479

High

192179

CP2C9
Cytochrome P450 2C9

1

1

High-throughput

0.479

High

192181

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

192182

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.479

High

192183

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

192186

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

192188

CXA1
Gap junction alpha-1 protein

1

8

High-throughput

0.479

High

192189

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

192190

RAB3B
Ras-related protein Rab-3B

1

5

High-throughput

0.479

High

192191

RAB4A
Ras-related protein Rab-4A

1

11

High-throughput

0.479

High

192192

RAB5A
Ras-related protein Rab-5A

1

8

High-throughput

0.479

High

192194

FGFR4
Fibroblast growth factor receptor 4

1

9

High-throughput

0.479

High

192196

CALX
Calnexin

1

2

High-throughput

0.479

High

192197

EPHA8
Ephrin type-A receptor 8

1

4

High-throughput

0.479

High

192198

EPHB2
Ephrin type-B receptor 2

1

7

High-throughput

0.479

High

192199

MARCS
Myristoylated alanine-rich C-kinase substrate

1

4

High-throughput

0.479

High

192200

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

1

High-throughput

0.479

High

192201

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

192202

CTNA1
Catenin alpha-1

1

1

Small-scale

0.479

High

192205

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.479

High

192206

ARL1
ADP-ribosylation factor-like protein 1

1

6

High-throughput

0.479

High

192207

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

192209

SSRA
Translocon-associated protein subunit alpha

1

1

High-throughput

0.479

High

192211

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

192214

EMD
Emerin

1

1

High-throughput

0.479

High

192215

RAB5C
Ras-related protein Rab-5C

1

8

High-throughput

0.479

High

192216

RAB7A
Ras-related protein Rab-7a

1

13

High-throughput

0.479

High

192217

RAB9A
Ras-related protein Rab-9A

1

13

High-throughput

0.479

High

192218

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

192220

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

192223

AFAD
Afadin

1

1

High-throughput

0.479

High

192224

ARL4C
ADP-ribosylation factor-like protein 4C

1

12

High-throughput

0.479

High

192225

PEX3
Peroxisomal biogenesis factor 3

1

2

High-throughput

0.479

High

192226

RAB25
Ras-related protein Rab-25

1

6

High-throughput

0.479

High

192228

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.479

High

192229

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

192230

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

192231

RAB2A
Ras-related protein Rab-2A

1

9

High-throughput

0.479

High

192232

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

192233

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

192238

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

192239

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

192240

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

192241

REEP5
Receptor expression-enhancing protein 5

1

2

High-throughput

0.479

High

192242

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

192243

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

11

High-throughput

0.479

High

192245

CKAP4
Cytoskeleton-associated protein 4

1

3

High-throughput

0.479

High

192249

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.479

High

192250

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

2

High-throughput

0.479

High

192251

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

192253

EPHA7
Ephrin type-A receptor 7

1

3

High-throughput

0.479

High

192254

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.479

High

192255

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

192257

NTRK3
NT-3 growth factor receptor

1

15

High-throughput

0.479

High

192263

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

192265

RHDF2
Inactive rhomboid protein 2

1

3

High-throughput

0.479

High

192266

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

192267

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

192268

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

192269

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

192270

MAVS
Mitochondrial antiviral-signaling protein

1

2

High-throughput

0.479

High

192274

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.479

High

192276

TEX2
Testis-expressed protein 2

1

1

High-throughput

0.479

High

192278

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

192279

CXD3
Gap junction delta-3 protein

1

8

High-throughput

0.479

High

192280

ARL14
ADP-ribosylation factor-like protein 14

1

7

High-throughput

0.479

High

192282

ARL10
ADP-ribosylation factor-like protein 10

1

14

High-throughput

0.479

High

192283

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

192284

PDZD8
PDZ domain-containing protein 8

1

1

High-throughput

0.479

High

192285

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.479

High

192289

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

192290

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

7

High-throughput

0.479

High

192292

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.479

High

192293

LRC59
Leucine-rich repeat-containing protein 59

1

2

High-throughput

0.479

High

192295

TECT2
Tectonic-2

1

3

High-throughput

0.479

High

192297

DNJC1
DnaJ homolog subfamily C member 1

1

6

High-throughput

0.479

High

192298

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.479

High

192300

PANX1
Pannexin-1

1

1

High-throughput

0.479

High

192301

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

7

High-throughput

0.479

High

192302

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

192303

SEC62
Translocation protein SEC62

1

2

High-throughput

0.479

High

192304

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

192307

ESYT1
Extended synaptotagmin-1

1

3

High-throughput

0.479

High

192309

DERL1
Derlin-1

1

4

High-throughput

0.479

High

192310

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

192312

LNP
Endoplasmic reticulum junction formation protein lunapark

1

1

High-throughput

0.479

High

192316

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

192317

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

192319

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

192320

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

192321

DBLOH
Diablo IAP-binding mitochondrial protein

1

1

High-throughput

0.479

High

192322

PXMP2
Peroxisomal membrane protein 2

1

1

High-throughput

0.479

High

192326

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.479

High

192328

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

192331

ELOV5
Very long chain fatty acid elongase 5

1

3

High-throughput

0.479

High

192335

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.479

High

192336

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

192338

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

3

High-throughput

0.479

High

192340

SEC63
Translocation protein SEC63 homolog

1

3

High-throughput

0.479

High

192342

ALK
ALK tyrosine kinase receptor

1

14

High-throughput

0.479

High

192345

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.479

High

192347

FIS1
Mitochondrial fission 1 protein

1

1

High-throughput

0.479

High

192348

MTCH2
Mitochondrial carrier homolog 2

1

2

High-throughput

0.479

High

192153

MFN2
Mitofusin-2

1

0

High-throughput

0.458

High

192154

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

192160

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

192169

LYN
Tyrosine-protein kinase Lyn

1

0

High-throughput

0.458

High

192173

CLCA
Clathrin light chain A

1

0

High-throughput

0.458

High

192174

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

192176

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

192180

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

192184

EZRI
Ezrin

1

0

High-throughput

0.458

High

192208

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

192244

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

192252

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.458

High

192258

OCLN
Occludin

1

0

High-throughput

0.458

High

192261

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

192272

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

192287

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

192296

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

192299

FMNL2
Formin-like protein 2

1

0

High-throughput

0.458

High

192306

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

192327

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

192329

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

High-throughput

0.458

High

192333

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

75544

B3KSP9
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.445

High

192147

USO1
General vesicular transport factor p115

1

5

Small-scale

0.445

High

192260

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

192311

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

192334

IL36G
Interleukin-36 gamma

1

1

High-throughput

0.445

High

104871

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

192185

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

192193

LMNB1
Lamin-B1

1

7

High-throughput

0.437

High

192195

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

192203

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

192256

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.437

High

192264

TECT3
Tectonic-3

1

3

High-throughput

0.437

High

192273

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

192314

DJC25
DnaJ homolog subfamily C member 25

1

5

High-throughput

0.437

High

192315

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

192323

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.437

High

192346

DJC16
DnaJ homolog subfamily C member 16

1

3

High-throughput

0.437

High

192234

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

0

High-throughput

0.426

High

192294

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.426

High

192313

NAA50
N-alpha-acetyltransferase 50

1

0

High-throughput

0.426

High

192325

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

192344

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

192281

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

3

0

High-throughput

0.347

High

192318

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

192262

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

192291

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

192159

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low

192341

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025