HitPredict

Interactor 1: NEB2 (O35274)
Neurabin-2 (Neurabin-II) (Neural tissue-specific F-actin-binding protein II) (PP1bp134) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin) (p130)
Gene: Ppp1r9b

Interactor 2: KCC2A (P11275)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: Camk2a

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20124353
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0014069 - postsynaptic density GO:0030425 - dendrite GO:0043025 - neuronal cell body GO:0043197 - dendritic spine
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Rn			1 478
+	Mm
		515240 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2A_MOUSE (1-478): 0: 569: 100.00
+	Mm
		1161534 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2D_MOUSE (2-475): 0: 552: 87.55
+	Rn
		192513 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2D_RAT (2-475): 0: 535: 80.47
+	Mm
		1164026 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2G_MOUSE (1-475): 0: 525: 76.43
+	Rn
		192511 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2G_RAT (1-475): 0: 522: 75.95
+	Rn
		192509 NEB2_RAT (1-817): 4.47e-115: 370: 100.00		KCC2B_RAT (1-475): 3.83e-178: 512: 70.87
+	Mm
		659460 NEB2_MOUSE (1-817): 8.79e-114: 367: 98.90		KCC2B_MOUSE (1-475): 1.19e-178: 513: 71.06
+	Mm
		515234 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2A_MOUSE (1-478): 0: 569: 100.00
+	Mm
		1143346 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2D_MOUSE (2-475): 0: 552: 87.55
+	Rn
		506715 LRRC7_RAT (5-586): 1.44e-40: 164: 15.11		KCC2A_RAT (1-478): 0: 569: 100.00
+	Mm
		1131547 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		Q5SVI3_MOUSE (1-475): 0: 533: 78.64
+	Hs
		1021591 DLG1_HUMAN (43-803): 4.57e-35: 145: 10.10		KCC2A_HUMAN (1-478): 0: 569: 99.79
+	Mm
		659457 DLG4_MOUSE (332-780): 3.04e-52: 196: 14.76		KCC2B_MOUSE (1-475): 1.19e-178: 513: 71.06
+	Rn
		506740 DLG1_RAT (43-697): 2.37e-31: 133: 10.54		KCC2A_RAT (1-478): 0: 569: 100.00
+	Hs
		159190 DLG4_HUMAN (332-780): 1.01e-51: 195: 14.76		CSKP_HUMAN (9-307): 2.56e-85: 283: 46.08
+	Hs
		159255 ERBIN_HUMAN (14-583): 2.28e-42: 169: 13.46		CSKP_HUMAN (9-307): 2.56e-85: 283: 46.08
+	Hs
		159200 DLG1_HUMAN (43-803): 4.57e-35: 145: 10.10		CSKP_HUMAN (9-307): 2.56e-85: 283: 46.08
+	Mm
		251104 DLG1_MOUSE (43-727): 7.64e-34: 141: 9.99		CSKP_MOUSE (9-307): 2.56e-85: 283: 46.08
+	Rn
		1144009 DLG1_RAT (43-697): 2.37e-31: 133: 10.54		CSKP_RAT (9-307): 2.45e-85: 282: 46.08
+	Hs
		108908 H0YKB7_HUMAN (277-650): 2.27e-42: 162: 16.88		KCC1A_HUMAN (13-306): 1.72e-72: 235: 42.86