HitPredict

Interactor 1: SRBS2 (O35413)
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Neural ArgBP2) (nArgBP2) (Sorbin)
Gene: Sorbs2

Interactor 2: DYN2 (P39052)
Dynamin-2 (EC 3.6.5.5)
Gene: Dnm2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	15659545
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PH~SH3_1, PH~SH3_9
Common GO terms	GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0045202 - synapse GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1196 Rn			1 870
+	Rn
		192739 SRBS2_RAT (1-1196): 0: 900: 100.00		DYN1_RAT (1-847): 0: 1011: 78.71
+	Hs
		282319 NEBL_HUMAN (178-1196): 3.24e-55: 211: 11.87		DYN2_HUMAN (1-870): 0: 1079: 98.05
+	Hs
		840811 SRBS1_HUMAN (71-1196): 6.94e-50: 195: 14.24		DYN2_HUMAN (1-870): 0: 1079: 98.05
+	Hs
		840840 ITSN2_HUMAN (53-1101): 1.05e-43: 176: 11.66		DYN2_HUMAN (1-870): 0: 1079: 98.05
+	Mm
		760474 GRB2_MOUSE (820-1019): 1.37e-19: 90.6: 18.50		DYN2_MOUSE (1-870): 0: 1088: 99.66
+	Hs
		840683 MYO1E_HUMAN (970-1196): 2.26e-19: 96.6: 15.20		DYN2_HUMAN (1-870): 0: 1079: 98.05
+	Mm
		760488 ITSN1_MOUSE (203-1027): 4.84e-16: 86.2: 10.01		DYN2_MOUSE (1-870): 0: 1088: 99.66
+	Hs
		840663 GRB2_HUMAN (820-1019): 2.27e-19: 90.2: 18.50		DYN2_HUMAN (1-870): 0: 1079: 98.05
+	Mm
		223006 NCK2_MOUSE (921-1133): 6.69e-28: 119: 19.56		DYN1_MOUSE (1-868): 0: 1033: 77.74
+	Hs
		209034 NCK2_HUMAN (921-1133): 5.55e-28: 119: 19.56		DYN1_HUMAN (1-847): 0: 1019: 79.18
+	Mm
		760450 GRB2_MOUSE (820-1019): 1.37e-19: 90.6: 18.50		DYN1_MOUSE (1-868): 0: 1033: 77.74
+	Mm
		760469 ITSN1_MOUSE (203-1027): 4.84e-16: 86.2: 10.01		DYN1_MOUSE (1-868): 0: 1033: 77.74
+	Hs
		983372 MYO1E_HUMAN (970-1196): 2.26e-19: 96.6: 15.20		DYN1_HUMAN (1-847): 0: 1019: 79.18
+	Mm
		1141147 GRB2_MOUSE (820-1019): 1.37e-19: 90.6: 18.50		DYN3_MOUSE (1-870): 0: 1022: 78.06
+	Hs
		924499 GRB2_HUMAN (820-1019): 2.27e-19: 90.2: 18.50		DYN1_HUMAN (1-847): 0: 1019: 79.18
+	Hs
		924956 GRB2_HUMAN (820-1019): 2.27e-19: 90.2: 18.50		DYN3_HUMAN (1-870): 0: 1016: 78.22
+	Rn
		599402 GRB2_RAT (820-1019): 2.27e-19: 90.2: 18.50		DYN1_RAT (1-847): 0: 1011: 78.71
+	Dm
		112570 M9ND00_DROME (339-1195): 2.87e-23: 109: 10.90		DYN_DROME (6-854): 0: 953: 65.70
+	Dm
		247616 O61618_DROME (339-1195): 1.54e-22: 106: 11.79		DYN_DROME (6-854): 0: 953: 65.70
+	Ce
		711198 YKA7_CAEEL (933-1195): 4.96e-25: 112: 20.44		DYN1_CAEEL (3-762): 0: 937: 66.40