Interactor 1: TRPV1 (O35433)
Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like)
Gene: TRPV1

Interactor 2: TRPV1 (O35433)
Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1) (Vanilloid receptor type 1-like)
Gene: TRPV1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.951

The method score is based on:

Property Details
Experiments 18490661, 24305160, 24305161, 27281200, 34239123, 22575650
Identification Methods molecular sieving, 3D electron microscopy, transmission electron microscopy, electron microscopy 3D single particle reconstruction, dynamic light scattering, static light scattering, comigration in non denaturing gel electrophoresis, cross-linking study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank, Ank~Ank_2, Ank_2~Ank_2, Ion_trans~Ion_trans
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001659 - temperature homeostasis
GO:0001660 - fever generation
GO:0001774 - microglial cell activation
GO:0002024 - diet induced thermogenesis
and 62 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 838
Rn

1 838
+ Mm
+ Hs
+ Mm
+ Hs
+ Rn
+ Oc
+ Mm
+ Hs
+ Hs
+ Rn
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024