Interactor 1: SOCS3 (O35718)
Suppressor of cytokine signaling 3 (SOCS-3) (Cytokine-inducible SH2 protein 3) (CIS-3) (Protein EF-10)
Gene: SOCS3
Interactor 2: PTN11 (P35235)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)
Gene: Ptpn11
Species: Mus musculus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.39 | 1.00 | 0.625 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12403768 |
| Identification Methods | pull down, surface plasmon resonance |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH2, SH2~Y_phosphatase |
| Common GO terms | GO:0001784 - phosphotyrosine residue binding GO:0005829 - cytosol GO:0007165 - signal transduction |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
