HitPredict

Interactor 1: RRP41 (O42872)
Exosome complex component ski6 (Ribosomal RNA-processing protein 41)
Gene: ski6

Interactor 2: DIS3 (P37202)
Exosome complex exonuclease dis3 (EC 3.1.13.-) (EC 3.1.26.-) (Chromosome disjunction protein 3) (Mitotic control protein dis3) (Ribosomal RNA-processing protein 44)
Gene: DIS3

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 30321377, 23503588
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains OB_Dis3~RNase_PH, RNB~RNase_PH, OB_Dis3~RNase_PH_C
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000785 - chromatin
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 242
Sp

1 970
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+ Dm
+ At
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+ Dm
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+ Pf

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Last updated: 15 Jul 2024