HitPredict

Interactor 1: FES1 (O43030)
Hsp70 nucleotide exchange factor fes1
Gene: FES1

Interactor 2: HSP71 (Q10265)
Probable heat shock protein ssa1
Gene: ssa1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	26771498, 23695164
Identification Methods	two hybrid, protein complementation assay, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 287 Sp			1 644
+	Sc
		605341 FES1_YEAST (1-272): 6.44e-66: 209: 27.97		HSP74_YEAST (1-644): 0: 967: 79.35
+	Sc
		493800 FES1_YEAST (1-272): 6.44e-66: 209: 27.97		HSP72_YEAST (1-644): 0: 949: 79.66
+	Sc
		491027 FES1_YEAST (1-272): 6.44e-66: 209: 27.97		HSP71_YEAST (1-610): 0: 940: 80.82
+	Hs
		714085 HPBP1_HUMAN (1-246): 3.76e-59: 194: 19.77		HS71L_HUMAN (2-644): 0: 947: 73.10
+	Hs
		504872 HPBP1_HUMAN (1-246): 3.76e-59: 194: 19.77		HSP7C_HUMAN (2-644): 0: 946: 75.12
+	Hs
		564199 HPBP1_HUMAN (1-246): 3.76e-59: 194: 19.77		HSP76_HUMAN (4-644): 0: 943: 69.89
+	Hs
		483807 HPBP1_HUMAN (1-246): 3.76e-59: 194: 19.77		HS71B_HUMAN (2-644): 0: 933: 74.34
+	Hs
		871809 HPBP1_HUMAN (1-246): 3.76e-59: 194: 19.77		HSP72_HUMAN (2-610): 0: 926: 77.09
+	Hs
		134830 IMA3_HUMAN (28-272): 2.45e-25: 106: 13.66		HSP7C_HUMAN (2-644): 0: 946: 75.12
+	Hs
		503727 IMA1_HUMAN (35-250): 2.72e-17: 83.6: 12.16		HSP7C_HUMAN (2-644): 0: 946: 75.12
+	Sc
		492201 IMA1_YEAST (5-229): 1.51e-16: 81.3: 14.77		HSP71_YEAST (1-610): 0: 940: 80.82
+	Sp
		293250 IMA2_SCHPO (33-235): 1.93e-17: 84: 11.77		HSP71_SCHPO (1-644): 0: 934: 100.00