HitPredict

Interactor 1: FLRT2 (O43155)
Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin-like domain-containing leucine-rich transmembrane protein 2)
Gene: FLRT2

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~fn3
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005925 - focal adhesion GO:0043005 - neuron projection and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 660 Hs			1 191
+	Hs
		195850 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		195866 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		195859 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		195860 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		195857 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		195849 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		195848 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		195855 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		195863 FLRT2_HUMAN (1-660): 2.14e-140: 426: 100.00		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82
+	Hs
		951411 FLRT3_HUMAN (9-660): 3.5e-123: 381: 44.06		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		564572 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		1150801 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925357 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		894129 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		951079 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		900582 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545442 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436360 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		892431 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		1150759 VASN_HUMAN (33-532): 1.86e-78: 265: 22.46		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82