HitPredict

Interactor 1: TTI1 (O43156)
TELO2-interacting protein 1 homolog (Protein SMG10)
Gene: TTI1

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 20810650, 20427287, 34171383, 22544753
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031931 - TORC1 complex
GO:0031932 - TORC2 complex
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1089
Hs

1 2549
+ Dm
+ Sp
+ At
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Sp
+ Sp
+ Sp
+ Sc
+ Sp
+ Sc

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Last updated: 15 Jul 2024