Protein: NEDD4
E3 ubiquitin-protein ligase Nedd-4 (DNedd4) (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4)

Gene: NEDD4
Organism: Drosophila melanogaster
Interactions: 25
UniProt ID: Q9VVI3

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0002092 - positive regulation of receptor internalization
GO:0004842 - ubiquitin-protein transferase activity
GO:0005112 - Notch binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

577405

PTC
Protein patched

4

13

Small-scale

0.677

High

1096141

COMM
Protein commissureless 1

4

0

Small-scale

0.667

High

1374788

SUDX
E3 ubiquitin-protein ligase Su(dx)

1

15

High-throughput

0.618

High

1180693

Q7KLE5
Amphiphysin

2

8

Small-scale

0.614

High

1341922

Q9NCC3
Sorting nexin

2

3

Small-scale

0.584

High

1001788

Q0KHU0
Myosin 10A, isoform D

1

4

Small-scale

0.552

High

247208

TENM
Teneurin-m

1

13

High-throughput

0.484

High

1367276

Q9VHK4
Polychaetoid, isoform B

1

13

Small-scale

0.481

High

219742

SPY
Protein sprouty

1

3

High-throughput

0.479

High

422918

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

13

Small-scale

0.479

High

1249345

Q8SYU5
RE33762p

1

20

High-throughput

0.479

High

1363736

Q9VDI1
LD46328p

1

5

Small-scale

0.479

High

1366431

Q9VGU4
FI02822p

1

20

High-throughput

0.479

High

1367606

Q9VHZ7
LD29844p

1

20

High-throughput

0.479

High

1367624

Q9VI00
FI24305p1

1

20

High-throughput

0.479

High

1374786

Q9VVJ5
Nedd4 family interacting protein

1

17

Small-scale

0.479

High

1366255

Q9VGN4
Sarcomere length short, isoform B

1

7

High-throughput

0.445

High

1368950

Q9VJW9
ADAM10 endopeptidase

1

2

High-throughput

0.445

High

1374327

FRL
Formin-like protein

1

3

High-throughput

0.437

High

1095979

DALY
Division abnormally delayed protein

1

0

High-throughput

0.426

High

1212527

Q8IGE8
RH36596p

1

1

High-throughput

0.417

High

1364143

INO80
Chromatin-remodeling ATPase INO80

1

6

High-throughput

0.407

High

1374787

Q9W0L7
ubiquitinyl hydrolase 1

1

14

High-throughput

0.407

High

1179498

Q7K3C2
LD38554p

1

0

High-throughput

0.249

Low

1360778

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024