HitPredict

Interactor 1: PLXB1 (O43157)
Plexin-B1 (Semaphorin receptor SEP)
Gene: PLXNB1

Interactor 2: RND2 (P52198)
Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)
Gene: RND2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 12730235, 22807448, 29040270
Identification Methods pull down, affinity chromatography technology, isothermal titration calorimetry, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Plexin_cytopl~Ras, Plexin_RBD~Ras, Ras~TIG
Common GO terms GO:0005886 - plasma membrane
GO:0016477 - cell migration
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2135
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024