HitPredict

Interactor 1: PLXB1 (O43157)
Plexin-B1 (Semaphorin receptor SEP)
Gene: PLXNB1

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.890

The method score is based on:

Property Details
Experiments 12730235, 22807448, 14732713, 29040270
Identification Methods pull down, affinity chromatography technology, affinity technology, isothermal titration calorimetry, molecular sieving
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Plexin_cytopl~Ras, Plexin_RBD~Ras, Ras~TIG
Common GO terms GO:0005886 - plasma membrane
GO:0016477 - cell migration
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2135
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024