HitPredict

Interactor 1: PJA2 (O43164)
E3 ubiquitin-protein ligase Praja-2 (Praja2) (EC 2.3.2.27) (RING finger protein 131) (RING-type E3 ubiquitin transferase Praja-2)
Gene: PJA2

Interactor 2: UB2J1 (Q9Y385)
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)
Gene: UBE2J1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 708 Hs			1 318
+	Hs
		196294 PJA2_HUMAN (1-708): 0: 580: 100.00		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		196372 PJA2_HUMAN (1-708): 0: 580: 100.00		UB2D4_HUMAN (10-156): 3.97e-70: 216: 28.00
+	Hs
		196282 PJA2_HUMAN (1-708): 0: 580: 100.00		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	Hs
		196289 PJA2_HUMAN (1-708): 0: 580: 100.00		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		919792 PJA1_HUMAN (12-681): 2.38e-128: 396: 42.92		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		895852 PJA1_HUMAN (12-681): 2.38e-128: 396: 42.92		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	Hs
		1245284 PJA1_HUMAN (12-681): 2.38e-128: 396: 42.92		UB2E3_HUMAN (2-156): 9.16e-63: 199: 26.58
+	At
		96605 F4IQ07_ARATH (145-687): 4.23e-61: 217: 14.34		UBC9_ARATH (10-156): 3.55e-67: 208: 29.33
+	At
		96610 F4IQ07_ARATH (145-687): 4.23e-61: 217: 14.34		UBC29_ARATH (10-157): 7.35e-66: 205: 26.49
+	At
		715138 Q8VYL4_ARATH (145-687): 1.69e-56: 203: 14.34		UBC9_ARATH (10-156): 3.55e-67: 208: 29.33
+	At
		1258030 Q8VYL4_ARATH (145-687): 1.69e-56: 203: 14.34		UBC29_ARATH (10-157): 7.35e-66: 205: 26.49
+	Hs
		919877 RNF12_HUMAN (124-679): 2.25e-50: 188: 15.36		UB2D2_HUMAN (10-156): 5.15e-70: 216: 28.00
+	Hs
		849459 RNF12_HUMAN (124-679): 2.25e-50: 188: 15.36		UB2D1_HUMAN (10-156): 1e-69: 215: 30.00
+	At
		249815 O65539_ARATH (407-702): 2.39e-56: 201: 15.81		UBC32_ARATH (2-316): 1.57e-61: 199: 36.45
+	Hs
		895927 RNF12_HUMAN (124-679): 2.25e-50: 188: 15.36		UB2D3_HUMAN (10-156): 1.73e-68: 212: 28.00
+	At
		249819 O65539_ARATH (407-702): 2.39e-56: 201: 15.81		UBC34_ARATH (12-150): 9.26e-59: 190: 44.29
+	Hs
		851893 RNF12_HUMAN (124-679): 2.25e-50: 188: 15.36		UB2E1_HUMAN (1-156): 1.67e-64: 203: 28.30
+	At
		1257797 Q8VY23_ARATH (407-702): 3.96e-53: 191: 15.81		UBC32_ARATH (2-316): 1.57e-61: 199: 36.45
+	Hs
		1297371 RNF12_HUMAN (124-679): 2.25e-50: 188: 15.36		UB2E2_HUMAN (2-156): 2.19e-62: 198: 27.22
+	At
		1257800 Q8VY23_ARATH (407-702): 3.96e-53: 191: 15.81		UBC34_ARATH (12-150): 9.26e-59: 190: 44.29