Interactor 1: PRP4 (O43172)
U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4)
Gene: PRPF4
Interactor 2: PPIH (O43447)
Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)
Gene: PPIH
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.970 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29997244, 33961781, 19615732, 16723661, 22365833, 27173435, 12875835, 12907720 |
| Identification Methods | fluorescent resonance energy transfer, affinity chromatography technology, two hybrid, x-ray crystallography, pull down, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRP4~Pro_isomerase |
| Common GO terms | GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0016607 - nuclear speck GO:0046540 - U4/U6 x U5 tri-snRNP complex and 1 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
