HitPredict

Interactor 1: O18332 (O18332)
FI01544p (Rab1)
Gene: Rab1

Interactor 2: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 205 Dm			1 184
+	Hs
		956706 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81
+	Hs
		956786 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RAB1B_HUMAN (4-179): 2.41e-76: 228: 31.07
+	Mm
		956826 RAB10_MOUSE (8-205): 5.24e-95: 276: 54.04		RAB1B_MOUSE (4-179): 5.91e-76: 227: 31.07
+	Hs
		956768 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RAB1C_HUMAN (4-179): 9.72e-75: 224: 31.64
+	Zm
		77342 B4FAE1_MAIZE (4-205): 3.4e-89: 262: 73.27		B4FAE1_MAIZE (4-179): 1.91e-79: 236: 35.59
+	Hs
		981254 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB1A_HUMAN (4-170): 8.44e-77: 229: 34.52
+	Hs
		976188 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RB11A_HUMAN (4-179): 8.48e-76: 228: 28.81
+	Hs
		981357 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB1B_HUMAN (4-179): 2.41e-76: 228: 31.07
+	Mm
		981416 RAB1A_MOUSE (1-205): 1.59e-90: 265: 82.93		RAB1B_MOUSE (4-179): 5.91e-76: 227: 31.07
+	Hs
		981287 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RB11B_HUMAN (4-176): 2.43e-74: 224: 29.89
+	Hs
		956239 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RAB2A_HUMAN (4-170): 1.01e-73: 222: 38.10
+	Hs
		902221 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RAB13_HUMAN (4-178): 2.09e-76: 228: 34.09
+	Hs
		1155389 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RB11B_HUMAN (4-176): 2.43e-74: 224: 29.89
+	Hs
		956483 RAB1B_HUMAN (4-205): 2.75e-86: 254: 83.17		RAB2A_HUMAN (4-170): 1.01e-73: 222: 38.10
+	Hs
		374507 RAB10_HUMAN (8-205): 5.24e-95: 276: 54.04		RASH_HUMAN (1-171): 3.86e-56: 177: 56.73
+	Hs
		375365 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RASK_HUMAN (1-182): 1.15e-56: 178: 55.50
+	Hs
		374510 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RASH_HUMAN (1-171): 3.86e-56: 177: 56.73
+	Hs
		373866 RAB1A_HUMAN (1-205): 1.59e-90: 265: 82.93		RASN_HUMAN (1-171): 2.96e-55: 174: 57.31