Protein: RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)

Gene: RPAB4, POLR2K
Organism: Homo sapiens
Interactions: 145
UniProt ID: P53803

Gene Ontology (top 5):
GO:0001054 - RNA polymerase I activity
GO:0001055 - RNA polymerase II activity
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317096

RPA1
DNA-directed RNA polymerase I subunit RPA1

4

9

Small-scale

0.895

High

624826

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

9

Small-scale

0.890

High

583440

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

4

Small-scale

0.853

High

676844

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

6

Small-scale

0.853

High

865003

RPC2
DNA-directed RNA polymerase III subunit RPC2

3

6

Small-scale

0.839

High

156007

RPC1
DNA-directed RNA polymerase III subunit RPC1

2

9

High-throughput

0.789

High

169819

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

4

High-throughput

0.789

High

864991

RPA2
DNA-directed RNA polymerase I subunit RPA2

2

6

High-throughput

0.789

High

854405

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

3

Small-scale

0.696

High

864942

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.691

High

864967

TF3B
Transcription factor IIIB 90 kDa subunit

1

3

High-throughput

0.691

High

583676

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

1

Small-scale

0.670

High

865002

RPC5
DNA-directed RNA polymerase III subunit RPC5

3

1

High-throughput

0.667

High

854281

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

1

Small-scale

0.660

High

864933

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

3

2

Small-scale

0.660

High

864935

RPB7
DNA-directed RNA polymerase II subunit RPB7

3

4

Small-scale

0.660

High

446551

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.656

High

577740

NELFE
Negative elongation factor E

1

0

High-throughput

0.656

High

726679

FUS
RNA-binding protein FUS

1

0

High-throughput

0.656

High

864946

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.656

High

181402

RPB4
DNA-directed RNA polymerase II subunit RPB4

2

1

High-throughput

0.628

High

864974

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

2

4

High-throughput

0.628

High

48642

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.628

High

225363

MED14
Mediator of RNA polymerase II transcription subunit 14

2

3

High-throughput

0.611

High

270189

RPC9
DNA-directed RNA polymerase III subunit RPC9

2

1

High-throughput

0.611

High

402723

RPC4
DNA-directed RNA polymerase III subunit RPC4

2

1

High-throughput

0.611

High

738832

RPB9
DNA-directed RNA polymerase II subunit RPB9

2

5

High-throughput

0.611

High

864937

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

1

High-throughput

0.611

High

864961

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

1

High-throughput

0.611

High

864981

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

1

High-throughput

0.611

High

864994

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

4

High-throughput

0.611

High

865018

RPC10
DNA-directed RNA polymerase III subunit RPC10

2

5

High-throughput

0.611

High

865021

RPC8
DNA-directed RNA polymerase III subunit RPC8

2

4

High-throughput

0.611

High

304599

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.586

High

179589

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.585

High

295609

RMP
Unconventional prefoldin RPB5 interactor 1

2

0

High-throughput

0.585

High

864944

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.585

High

864958

SPT6H
Transcription elongation factor SPT6

2

0

High-throughput

0.585

High

864977

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.585

High

864987

RPAP3
RNA polymerase II-associated protein 3

2

0

High-throughput

0.585

High

864993

MED4
Mediator of RNA polymerase II transcription subunit 4

2

0

High-throughput

0.585

High

865010

UXT
Protein UXT

2

0

High-throughput

0.585

High

864968

SH3K1
SH3 domain-containing kinase-binding protein 1

2

0

High-throughput

0.580

High

61755

BDP1
Transcription factor TFIIIB component B'' homolog

1

1

High-throughput

0.536

High

123886

SPT5H
Transcription elongation factor SPT5

1

2

High-throughput

0.536

High

131409

IMA4
Importin subunit alpha-4

1

1

High-throughput

0.536

High

175526

RPC7
DNA-directed RNA polymerase III subunit RPC7

1

1

High-throughput

0.536

High

534084

T2FB
General transcription factor IIF subunit 2

1

2

High-throughput

0.536

High

586634

CSK22
Casein kinase II subunit alpha'

1

2

High-throughput

0.536

High

589814

TBP
TATA-box-binding protein

1

1

High-throughput

0.536

High

672047

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.536

High

672391

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

1

High-throughput

0.536

High

722581

T2FA
General transcription factor IIF subunit 1

1

1

High-throughput

0.536

High

853210

IMA1
Importin subunit alpha-1

1

1

High-throughput

0.536

High

864938

SPT4H
Transcription elongation factor SPT4

1

1

High-throughput

0.536

High

864940

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

864947

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

1

High-throughput

0.536

High

864949

INT11
Integrator complex subunit 11

1

1

High-throughput

0.536

High

864976

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

1

1

High-throughput

0.536

High

864978

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.536

High

864984

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

1

High-throughput

0.536

High

864992

GPN1
GPN-loop GTPase 1

1

5

High-throughput

0.536

High

864997

INT9
Integrator complex subunit 9

1

1

High-throughput

0.536

High

865014

INT6
Integrator complex subunit 6

1

1

High-throughput

0.536

High

865016

RUVB2
RuvB-like 2

1

1

High-throughput

0.536

High

865017

RUVB1
RuvB-like 1

1

1

High-throughput

0.536

High

865022

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

128829

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

313410

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.513

High

448582

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

508413

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

538875

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

851232

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.513

High

864934

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

864939

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

High-throughput

0.513

High

864943

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

864945

IMB1
Importin subunit beta-1

1

0

High-throughput

0.513

High

864951

INT3
Integrator complex subunit 3

1

0

High-throughput

0.513

High

864954

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

864955

BRWD3
Bromodomain and WD repeat-containing protein 3

1

0

High-throughput

0.513

High

864957

INT8
Integrator complex subunit 8

1

0

High-throughput

0.513

High

864959

TRM1L
TRMT1-like protein

1

0

High-throughput

0.513

High

864960

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.513

High

864962

INT1
Integrator complex subunit 1

1

0

High-throughput

0.513

High

864963

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

864964

ZN655
Zinc finger protein 655

1

0

High-throughput

0.513

High

864965

NELFB
Negative elongation factor B

1

0

High-throughput

0.513

High

864969

INT12
Integrator complex subunit 12

1

0

High-throughput

0.513

High

864971

INT4
Integrator complex subunit 4

1

0

High-throughput

0.513

High

864975

INT14
Integrator complex subunit 14

1

0

High-throughput

0.513

High

864979

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.513

High

864982

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

1

0

High-throughput

0.513

High

864983

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

864986

NELFA
Negative elongation factor A

1

0

High-throughput

0.513

High

864995

SOSSC
SOSS complex subunit C

1

0

High-throughput

0.513

High

864999

INT7
Integrator complex subunit 7

1

0

High-throughput

0.513

High

865000

INT13
Integrator complex subunit 13

1

0

High-throughput

0.513

High

865001

INT10
Integrator complex subunit 10

1

0

High-throughput

0.513

High

865004

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.513

High

865007

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.513

High

865012

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.513

High

865015

TTF2
Transcription termination factor 2

1

0

High-throughput

0.513

High

865019

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.513

High

864948

INT6L
Integrator complex subunit 6-like

1

1

High-throughput

0.489

High

864990

GPN2
GPN-loop GTPase 2

1

5

High-throughput

0.489

High

865013

GPN3
GPN-loop GTPase 3

1

5

High-throughput

0.489

High

394392

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

864931

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

Small-scale

0.480

High

865020

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

162538

XPO1
Exportin-1

1

1

High-throughput

0.479

High

346313

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379160

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

864936

H4
Histone H4

1

1

High-throughput

0.479

High

864950

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

2

High-throughput

0.479

High

865008

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

5

High-throughput

0.479

High

244164

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

295514

RECQ5
ATP-dependent DNA helicase Q5

1

0

High-throughput

0.458

High

373930

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

532445

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

823748

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

864953

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

864966

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

864970

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

864985

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.458

High

864988

SFR19
Splicing factor, arginine/serine-rich 19

1

0

High-throughput

0.458

High

864989

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.458

High

864998

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.458

High

865006

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

865011

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

484440

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

3

High-throughput

0.445

High

473899

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.426

High

864932

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.426

High

864973

DAA10
Dynein axonemal assembly factor 10

2

0

High-throughput

0.318

High

864996

PDRG1
p53 and DNA damage-regulated protein 1

2

0

High-throughput

0.318

High

864952

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

2

0

High-throughput

0.305

High

171591

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.279

Low

864941

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

0

High-throughput

0.279

Low

864980

TNG6
Transport and Golgi organization protein 6 homolog

1

0

High-throughput

0.279

Low

865009

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.279

Low

473857

MYZAP
Myocardial zonula adherens protein

1

0

High-throughput

0.249

Low

864956

SEML
Putative protein SEM1, isoform 2

1

0

High-throughput

0.249

Low

865005

ASND1
Asparagine synthetase domain-containing protein 1

1

0

High-throughput

0.249

Low

112041

ASURF
ASNSD1 upstream open reading frame protein

1

0

High-throughput

0.232

Low

864972

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024