HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36147463
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 639
+	Hs
		197182 SERA_HUMAN (1-533): 0: 667: 100.00		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		197211 SERA_HUMAN (1-533): 0: 667: 100.00		K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48
+	Hs
		197181 SERA_HUMAN (1-533): 0: 667: 100.00		K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22
+	Hs
		197172 SERA_HUMAN (1-533): 0: 667: 100.00		K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22
+	Hs
		380603 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		729075 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		K22E_HUMAN (1-517): 4.22e-68: 235: 100.00