Protein: RAB5
Ras-related protein Rab5 (Drab5) (EC 3.6.5.2) (Small monomeric GTPase Rab5)

Gene: RAB5
Organism: Drosophila melanogaster
Interactions: 118
UniProt ID: Q9V3I2

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1463772

Q9VLS5
LD29542p

3

20

Small-scale

0.827

High

1463760

Q9VDJ9
non-specific serine/threonine protein kinase

2

16

Small-scale

0.776

High

1273736

Q7PLP5
Uncharacterized protein, isoform C

2

3

Small-scale

0.754

High

1321016

SPRI
Protein sprint

2

20

Small-scale

0.754

High

1463771

Q9VLB7
Rab GDP dissociation inhibitor

2

20

High-throughput

0.754

High

1463799

Q9W2M0
LD23155p

2

20

Small-scale

0.754

High

197248

RAB6
Ras-related protein Rab6

2

19

High-throughput

0.737

High

1463778

MON1
Vacuolar fusion protein MON1 homolog

2

0

Small-scale

0.718

High

197081

O18332
FI01544p

1

19

High-throughput

0.618

High

197160

RAB2
Ras-related protein Rab-2

1

20

High-throughput

0.618

High

235012

O46094
EG:86E4.5 protein

1

19

High-throughput

0.618

High

304134

RAB7
Ras-related protein Rab7

1

18

High-throughput

0.618

High

473566

RAP1
Ras-related protein Rap1

1

19

High-throughput

0.618

High

1174304

Q24468
Serine/threonine-protein kinase receptor

1

8

Small-scale

0.618

High

1265734

Q7K3H0
LD28067p

1

20

Small-scale

0.618

High

1268889

SCRIB
Protein lap4

1

7

Small-scale

0.618

High

1377995

Q95SI0
receptor protein serine/threonine kinase

1

8

Small-scale

0.618

High

1463750

WARTS
Serine/threonine-protein kinase Warts

1

7

High-throughput

0.618

High

1463762

Q9VFV9
DnaJ-like-2, isoform A

1

6

High-throughput

0.618

High

1463763

IPO9
Importin-9

1

2

High-throughput

0.618

High

1463786

DOME
Cytokine receptor

1

6

Small-scale

0.618

High

1463796

Q9W0H9
Rabaptin-5-associated exchange factor for Rab5

1

20

High-throughput

0.618

High

1463798

Q9W1M7
Phosphatidylinositol 3-kinase catalytic subunit type 3

1

18

High-throughput

0.618

High

1463806

X2JE40
Rho-associated protein kinase let-502

1

15

High-throughput

0.618

High

594795

GNAO
G protein alpha o subunit

2

5

Small-scale

0.600

High

1463795

CCZ1
Vacuolar fusion protein CCZ1 homolog

1

0

High-throughput

0.586

High

1463776

GOLP3
Golgi phosphoprotein 3 homolog sauron

2

2

Small-scale

0.584

High

304232

ERD2
ER lumen protein-retaining receptor

2

2

High-throughput

0.571

High

652069

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

12

High-throughput

0.571

High

958883

ARF1
ADP-ribosylation factor 1

2

20

High-throughput

0.571

High

1463748

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

6

High-throughput

0.571

High

1463767

ARL8
ADP-ribosylation factor-like protein 8

2

18

High-throughput

0.571

High

1463781

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

2

High-throughput

0.571

High

1463783

Q9VUZ0
Translocon-associated protein subunit beta

2

3

High-throughput

0.571

High

1463789

Q9VWL0
Mec2

2

9

High-throughput

0.571

High

1463794

Q9VZL3
very-long-chain enoyl-CoA reductase

2

2

High-throughput

0.571

High

1070921

Q0KI67
Myosin heavy chain-like, isoform G

1

4

High-throughput

0.553

High

1463759

Q9VDD5
Common Dpr-interacting protein

1

2

High-throughput

0.553

High

1463766

Q9VHH2
non-specific serine/threonine protein kinase

1

8

High-throughput

0.553

High

1463773

Q9VPL5
TBC1 domain family member 15

1

20

High-throughput

0.553

High

1463797

Q9W0K9
LD10220p

1

9

High-throughput

0.553

High

1463802

Q9W4F8
LD42868p

1

17

High-throughput

0.553

High

1176087

DX39B
ATP-dependent RNA helicase WM6

2

2

High-throughput

0.521

High

1463754

Q9VAW3
glutamine--fructose-6-phosphate transaminase

2

2

High-throughput

0.521

High

52683

A1Z729
NADP-retinol dehydrogenase

1

6

High-throughput

0.479

High

56276

A1ZA18
Kinesin heavy chain 73, isoform A

1

9

High-throughput

0.479

High

94130

D5AEK7
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform E

1

2

High-throughput

0.479

High

95046

E1JH23
Oxysterol-binding protein

1

11

High-throughput

0.479

High

121006

M9PEK6
Mushroom body defect, isoform L

1

8

Small-scale

0.479

High

615264

FRIZ
Frizzled

1

3

Small-scale

0.479

High

654311

DDX6
ATP-dependent RNA helicase me31b

1

2

High-throughput

0.479

High

715131

CLH
Clathrin heavy chain

1

4

High-throughput

0.479

High

1172877

HOOK
Protein hook

1

12

High-throughput

0.479

High

1173482

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

16

High-throughput

0.479

High

1173560

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

5

High-throughput

0.479

High

1176293

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

9

High-throughput

0.479

High

1202347

Q59DV6
Spermathreecae, isoform G

1

4

High-throughput

0.479

High

1260756

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

8

High-throughput

0.479

High

1264519

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

6

High-throughput

0.479

High

1265908

Q7K3K5
LD22804p

1

12

High-throughput

0.479

High

1267387

Q7KLX3
Translocon-associated protein subunit delta

1

2

High-throughput

0.479

High

1267698

Q7KMQ0
26S proteasome regulatory subunit 7

1

1

High-throughput

0.479

High

1269240

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

5

High-throughput

0.479

High

1306032

Q8IR93
Dynein light intermediate chain

1

3

Small-scale

0.479

High

1343131

Q8STG9
DSec61alpha

1

1

High-throughput

0.479

High

1376845

LDH
L-lactate dehydrogenase

1

3

High-throughput

0.479

High

1377640

FAXC
Failed axon connections

1

1

High-throughput

0.479

High

1463749

Q9V9Q4
LD43819p

1

2

High-throughput

0.479

High

1463752

Q9VAL7
Calnexin 99A, isoform A

1

5

High-throughput

0.479

High

1463755

Q9VAY2
Heat shock protein 83

1

12

High-throughput

0.479

High

1463757

Q9VC66
AT25567p

1

1

High-throughput

0.479

High

1463758

BECN1
Beclin-1-like protein

1

2

High-throughput

0.479

High

1463761

Q9VEV3
Tetratricopeptide repeat protein 1

1

5

High-throughput

0.479

High

1463764

Q9VHB5
Vacuolar protein sorting-associated protein 45

1

14

High-throughput

0.479

High

1463765

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

1

High-throughput

0.479

High

1463769

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

2

High-throughput

0.479

High

1463780

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

17

High-throughput

0.479

High

1463782

Q9VUH6
Myopic

1

6

Small-scale

0.479

High

1463805

VP33A
Vacuolar protein sorting-associated protein 33A

1

15

High-throughput

0.479

High

837157

MAD
Protein mothers against dpp

1

0

Small-scale

0.458

High

1306233

Q8IRD5
AT25231p

1

0

Small-scale

0.458

High

1463768

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.458

High

1463770

NFS1
Cysteine desulfurase, mitochondrial

1

0

High-throughput

0.458

High

1463785

ROGDI
Protein rogdi

1

0

High-throughput

0.458

High

1463792

Q9VXR6
GH09650p

1

0

High-throughput

0.458

High

119994

M9PC10
Uncharacterized protein, isoform G

1

19

High-throughput

0.437

High

144886

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.437

High

360558

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.437

High

477300

LAM0
Lamin Dm0

1

11

Small-scale

0.437

High

875252

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.437

High

1011979

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

1

High-throughput

0.437

High

1196000

Q4QQB9
LP21121p

1

1

High-throughput

0.437

High

1268164

Q7KN94
Electron transfer flavoprotein subunit alpha

1

1

High-throughput

0.437

High

1285540

Q86BB4
Transforming acidic coiled-coil protein, isoform E

1

3

High-throughput

0.437

High

1376891

CATL1
Cathepsin L1

1

4

High-throughput

0.437

High

1378461

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

6

High-throughput

0.437

High

1463747

Q9V3N4
Huntingtin, isoform A

1

9

High-throughput

0.437

High

1463756

Q9VBU5
3-dehydrosphinganine reductase

1

4

High-throughput

0.437

High

1463774

Q9VPR1
GH02075p

1

2

High-throughput

0.437

High

1463775

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

3

High-throughput

0.437

High

1463777

U518
FHIP family protein CG3558

1

6

High-throughput

0.437

High

1463784

Q9VV75
AT02348p

1

2

High-throughput

0.437

High

1463788

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.437

High

1463791

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

1

High-throughput

0.437

High

1463800

Q9W3N1
RH59310p

1

6

High-throughput

0.437

High

1463801

Q9W425
Rabconnectin-3A

1

9

High-throughput

0.437

High

1463803

Q9W543
Rabconnectin-3B, isoform A

1

11

High-throughput

0.437

High

1463751

FRIL
Ferritin light chain

1

0

High-throughput

0.426

High

1236872

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

8

High-throughput

0.407

High

1266264

Q7K485
Cathepsin D

2

0

High-throughput

0.298

High

1306664

SIR4
NAD-dependent protein deacylase Sirt4

1

0

High-throughput

0.265

Low

1237577

Q6NR46
Serine palmitoyltransferase 1

1

0

High-throughput

0.249

Low

1463753

Q9VAU6
LD27564p

1

0

High-throughput

0.249

Low

1463779

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.249

Low

1463787

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.249

Low

1463790

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

High-throughput

0.249

Low

1463793

NADE
Glutamine-dependent NAD(+) synthetase

1

0

High-throughput

0.249

Low

1463804

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025