HitPredict

Interactor 1: SERA (O43175)
D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)
Gene: PHGDH

Interactor 2: HDAC5 (Q9UQL6)
Histone deacetylase 5 (HD5) (EC 3.5.1.98) (Antigen NY-CO-9)
Gene: HDAC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21081666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 533 Hs			1 1122
+	Hs
		1032689 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC5_HUMAN (1-1122): 0: 727: 100.00
+	Hs
		197419 SERA_HUMAN (1-533): 0: 667: 100.00		HDAC6_HUMAN (599-1061): 7.06e-106: 362: 31.97
+	Hs
		880714 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC4_HUMAN (1-1101): 0: 653: 54.96
+	Hs
		1032674 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC9_HUMAN (25-1055): 0: 608: 56.33
+	Hs
		881167 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		881245 CTBP2_HUMAN (21-383): 8.27e-123: 369: 29.10		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Mm
		292164 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		HDAC2_MOUSE (680-1113): 4.65e-153: 467: 21.68
+	Hs
		1032389 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC1_HUMAN (673-1103): 1.54e-153: 468: 21.16
+	Hs
		1032538 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC2_HUMAN (680-1113): 1.34e-153: 468: 21.68
+	Mm
		292177 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		HDAC7_MOUSE (191-1122): 3.04e-139: 446: 37.55
+	Mm
		292181 CTBP1_MOUSE (1-384): 7.07e-121: 364: 28.89		HDAC9_MOUSE (25-633): 3.61e-142: 442: 47.10
+	Hs
		177284 CTBP1_HUMAN (21-384): 5.06e-120: 362: 29.89		HDAC3_HUMAN (679-1119): 5.97e-144: 441: 21.57