HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: FYN (P06241)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn)
Gene: FYN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25825872
Identification Methods	peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 909 Hs			1 537
+	Hs
		197583 ADA12_HUMAN (1-909): 0: 665: 100.00		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		197581 ADA12_HUMAN (1-909): 0: 665: 100.00		HCK_HUMAN (1-535): 0: 548: 56.64
+	Hs
		197580 ADA12_HUMAN (1-909): 0: 665: 100.00		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		523142 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		412180 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		FYN_HUMAN (1-537): 0: 643: 100.00
+	Hs
		442882 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		HCK_HUMAN (1-535): 0: 548: 56.64
+	Hs
		433747 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		522899 ADAM8_HUMAN (29-855): 4.63e-145: 452: 33.88		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		433995 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		522964 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SRC_HUMAN (1-537): 0: 598: 68.21
+	Hs
		433344 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		YES_HUMAN (1-537): 0: 591: 71.61
+	Hs
		442890 ADA22_HUMAN (3-863): 2.63e-147: 460: 26.40		HCK_HUMAN (1-535): 0: 548: 56.64
+	Hs
		788989 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		TEC_HUMAN (5-529): 6.12e-163: 478: 34.89
+	Hs
		434044 ADA22_HUMAN (3-863): 2.63e-147: 460: 26.40		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		789007 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		TEC_HUMAN (5-529): 6.12e-163: 478: 34.89
+	Hs
		411708 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		LCK_HUMAN (40-535): 0: 551: 57.60
+	Hs
		442824 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		HCK_HUMAN (1-535): 0: 548: 56.64
+	Hs
		433748 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		LYN_HUMAN (1-535): 0: 535: 54.48
+	Hs
		788983 ADAM8_HUMAN (29-855): 4.63e-145: 452: 33.88		TEC_HUMAN (5-529): 6.12e-163: 478: 34.89
+	Hs
		337463 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		ABL1_HUMAN (42-537): 7.36e-167: 504: 39.56