Protein: DACH1
Dachshund homolog 1 (Dach1)

Gene: DACH1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9UI36

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1399287

DACH2
Dachshund homolog 2

2

2

High-throughput

0.811

High

1460220

DACH1
Dachshund homolog 1

2

2

High-throughput

0.800

High

1460222

NAGK
N-acetyl-D-glucosamine kinase

5

0

High-throughput

0.694

High

1458702

RNF14
E3 ubiquitin-protein ligase RNF14

3

1

High-throughput

0.675

High

430478

JUN
Transcription factor Jun

3

1

Small-scale

0.658

High

230134

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

3

0

High-throughput

0.646

High

961232

FGF12
Fibroblast growth factor 12

3

0

High-throughput

0.646

High

999424

HBB
Hemoglobin subunit beta

3

0

High-throughput

0.629

High

993801

UBC9
SUMO-conjugating enzyme UBC9

2

0

Small-scale

0.602

High

1295379

GPSM1
G-protein-signaling modulator 1

2

0

High-throughput

0.602

High

1453531

SPN90
NCK-interacting protein with SH3 domain

2

0

High-throughput

0.602

High

1460221

SCOC
Short coiled-coil protein

2

0

High-throughput

0.602

High

278446

NCOR1
Nuclear receptor corepressor 1

2

2

Small-scale

0.601

High

474355

NFIC
Nuclear factor 1 C-type

2

3

High-throughput

0.595

High

1133721

NFIX
Nuclear factor 1 X-type

2

3

High-throughput

0.584

High

725473

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.580

High

1051531

SRS11
Serine/arginine-rich splicing factor 11

2

0

High-throughput

0.580

High

1106739

SMAD4
Mothers against decapentaplegic homolog 4

1

2

Small-scale

0.578

High

1145425

RNPS1
RNA-binding protein with serine-rich domain 1

2

0

High-throughput

0.576

High

1388062

TRI44
Tripartite motif-containing protein 44

2

2

High-throughput

0.574

High

685764

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.549

High

1105000

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.549

High

1460224

FOXA2
Hepatocyte nuclear factor 3-beta

1

4

High-throughput

0.536

High

1014647

SMAD3
Mothers against decapentaplegic homolog 3

1

2

Small-scale

0.515

High

1403044

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.515

High

187207

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

282995

FRAT2
GSK-3-binding protein FRAT2

1

0

High-throughput

0.513

High

612005

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

659628

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.513

High

697433

DCK
Deoxycytidine kinase

1

0

High-throughput

0.513

High

948959

CD81
CD81 antigen

1

0

High-throughput

0.513

High

1460225

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.513

High

767366

MERL
Merlin

1

1

High-throughput

0.501

High

833585

SOX3
Transcription factor SOX-3

1

3

High-throughput

0.501

High

1057478

SOX4
Transcription factor SOX-4

1

3

High-throughput

0.501

High

1085637

FOXO1
Forkhead box protein O1

1

4

High-throughput

0.501

High

1150269

TEAD2
Transcriptional enhancer factor TEF-4

1

1

High-throughput

0.501

High

1154020

SMAD1
Mothers against decapentaplegic homolog 1

1

2

High-throughput

0.501

High

162977

TERT
Telomerase reverse transcriptase

1

0

High-throughput

0.480

High

170409

AURKA
Aurora kinase A

1

0

High-throughput

0.480

High

373429

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.480

High

587534

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.480

High

1154470

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.480

High

133141

FOXE1
Forkhead box protein E1

1

4

High-throughput

0.479

High

143312

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

188383

HDAC3
Histone deacetylase 3

1

2

Small-scale

0.479

High

662293

PAX7
Paired box protein Pax-7

1

2

High-throughput

0.479

High

685378

PAX6
Paired box protein Pax-6

1

2

High-throughput

0.479

High

703213

TEAD1
Transcriptional enhancer factor TEF-1

1

1

High-throughput

0.479

High

775927

HNF1B
Hepatocyte nuclear factor 1-beta

1

3

High-throughput

0.479

High

776147

SOX5
Transcription factor SOX-5

1

3

High-throughput

0.479

High

832587

ETV3
ETS translocation variant 3

1

2

High-throughput

0.479

High

837103

ELK3
ETS domain-containing protein Elk-3

1

2

High-throughput

0.479

High

872852

SOX2
Transcription factor SOX-2

1

3

Small-scale

0.479

High

1024224

TFAM
Transcription factor A, mitochondrial

1

2

High-throughput

0.479

High

1033297

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

1088083

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1091168

FOXC1
Forkhead box protein C1

1

5

High-throughput

0.479

High

1091369

FOXL1
Forkhead box protein L1

1

4

High-throughput

0.479

High

1110158

HDAC1
Histone deacetylase 1

1

2

Small-scale

0.479

High

1141348

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1201967

BRDT
Bromodomain testis-specific protein

1

1

High-throughput

0.479

High

1405451

FEV
Protein FEV

1

2

High-throughput

0.479

High

1408312

FOXC2
Forkhead box protein C2

1

5

High-throughput

0.479

High

1449307

SALL1
Sal-like protein 1

1

1

High-throughput

0.479

High

1460226

ARI1
E3 ubiquitin-protein ligase ARIH1

1

1

High-throughput

0.479

High

191150

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

337407

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

414795

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

487860

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

519433

MYB
Transcriptional activator Myb

1

0

High-throughput

0.458

High

558475

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

593239

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

697286

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

725334

TLX1
T-cell leukemia homeobox protein 1

1

0

High-throughput

0.458

High

800154

COIL
Coilin

1

0

High-throughput

0.458

High

807611

IF4A3
Eukaryotic initiation factor 4A-III

1

0

High-throughput

0.458

High

834084

HNF4A
Hepatocyte nuclear factor 4-alpha

1

0

High-throughput

0.458

High

862527

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

887308

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.458

High

981166

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1052920

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.458

High

1083453

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.458

High

1097616

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1114588

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1123860

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

1313506

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1364003

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1452461

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1458758

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1460223

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1348989

ZCH10
Zinc finger CCHC domain-containing protein 10

2

0

High-throughput

0.335

High

1414004

MMTA2
Multiple myeloma tumor-associated protein 2

2

0

High-throughput

0.330

High

1412046

WDR83
WD repeat domain-containing protein 83

2

0

High-throughput

0.328

High

1208343

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1331875

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low

1384736

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

516137

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025