HitPredict

Interactor 1: ADA12 (O43184)
Disintegrin and metalloproteinase domain-containing protein 12 (ADAM 12) (EC 3.4.24.-) (Meltrin-alpha)
Gene: ADAM12

Interactor 2: SH319 (Q5HYK7)
SH3 domain-containing protein 19 (ADAM-binding protein Eve-1) (EEN-binding protein) (EBP)
Gene: SH3D19

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15280379
Identification Methods	anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 909 Hs			1 790
+	Hs
		197601 ADA12_HUMAN (1-909): 0: 665: 100.00		ITSN1_HUMAN (417-786): 3.11e-27: 121: 18.20
+	Hs
		197596 ADA12_HUMAN (1-909): 0: 665: 100.00		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Hs
		197624 ADA12_HUMAN (1-909): 0: 665: 100.00		ITSN2_HUMAN (680-790): 7.11e-16: 84.4: 24.78
+	Mm
		1141131 ADA12_MOUSE (29-909): 0: 614: 80.82		GRB2_MOUSE (498-718): 2.72e-24: 103: 20.27
+	Hs
		557788 ADA19_HUMAN (5-907): 4.52e-167: 513: 41.68		NCK1_HUMAN (414-659): 8.08e-29: 120: 19.93
+	Hs
		298977 ADAM9_HUMAN (36-774): 2.04e-173: 525: 37.50		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		1034763 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SH3R3_HUMAN (418-723): 9.67e-28: 122: 17.33
+	Hs
		1034753 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		ITSN1_HUMAN (417-786): 3.11e-27: 121: 18.20
+	Hs
		557680 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		NCK1_HUMAN (414-659): 8.08e-29: 120: 19.93
+	Hs
		924546 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Hs
		298978 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SRBS2_HUMAN (612-787): 2.26e-15: 82.6: 22.53
+	Hs
		1034759 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SH3R1_HUMAN (244-550): 1.54e-09: 63.7: 11.61
+	Hs
		1034771 ADA15_HUMAN (35-874): 1.09e-131: 418: 34.52		SRBS1_HUMAN (672-788): 2.98e-09: 62.8: 33.07
+	Ce
		106476 ADM2_CAEEL (109-861): 2.09e-105: 350: 27.94		YKA7_CAEEL (219-623): 1.04e-26: 116: 16.30
+	Hs
		152297 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		SH319_HUMAN (1-790): 3.57e-99: 327: 100.00
+	Hs
		152249 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		NCK1_HUMAN (414-659): 8.08e-29: 120: 19.93
+	Hs
		152272 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		GRB2_HUMAN (498-718): 1.8e-24: 104: 20.27
+	Hs
		152285 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		GRAP_HUMAN (501-719): 3.12e-22: 97.9: 25.91
+	Hs
		152212 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		GRAP2_HUMAN (305-554): 1.65e-16: 83.6: 15.20
+	Hs
		152209 ADA10_HUMAN (341-548): 1.11e-18: 93.2: 32.77		VINEX_HUMAN (621-788): 1.29e-13: 76.7: 18.82