HitPredict

Interactor 1: DC1L2 (O43237)
Cytoplasmic dynein 1 light intermediate chain 2 (Dynein light intermediate chain 2, cytosolic) (LIC-2) (LIC53/55)
Gene: DYNC1LI2

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34079125, 28718761, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule GO:0016020 - membrane and 1 others more... GO:0030286 - dynein complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 1278
+	Hs
		1051535 DC1L1_HUMAN (2-492): 0: 766: 62.43		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		198226 DC1L2_HUMAN (1-492): 0: 812: 100.00		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Hs
		675254 DC1L1_HUMAN (2-492): 0: 766: 62.43		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32