Interactor 1: NRP2 (O60462)
Neuropilin-2 (Vascular endothelial cell growth factor 165 receptor 2)
Gene: NRP2

Interactor 2: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 17595163, 10748121
Identification Methods pull down, cross-linking study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains F5_F8_type_C~VEGF_C
Common GO terms GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005576 - extracellular region
GO:0008201 - heparin binding
GO:0010595 - positive regulation of endothelial cell migration
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 931
Hs

1 395
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024