HitPredict

Interactor 1: KLK10 (O43240)
Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1)
Gene: KLK10

Interactor 2: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~Trypsin
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 276 Hs			1 399
+	Hs
		198339 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGHG2_HUMAN (1-399): 3.98e-103: 312: 90.48
+	Hs
		198340 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGHG3_HUMAN (1-399): 7.71e-97: 298: 83.86
+	Hs
		353615 KLK3_HUMAN (21-276): 2.29e-99: 293: 34.10		IGHG1_HUMAN (1-399): 4.54e-108: 325: 100.00
+	Hs
		198342 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		198343 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGHD_HUMAN (1-374): 3.51e-61: 205: 23.73
+	Hs
		354040 TRY3_HUMAN (29-276): 2.22e-108: 317: 36.40		IGHA1_HUMAN (1-374): 5.12e-63: 209: 29.85
+	Hs
		198341 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGHM_HUMAN (1-358): 2.62e-22: 100: 19.90
+	Hs
		82357 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGLL5_HUMAN (2-103): 7.8e-12: 66.3: 31.43
+	Hs
		198337 KLK10_HUMAN (1-276): 7.23e-113: 327: 100.00		IGKC_HUMAN (229-321): 1.52e-09: 57: 29.47