HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	1.00	0.656

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 390 Hs			1 475
+	Hs
		198898 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		198880 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		641756 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		516364 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Zm
		111724 K7TYT2_MAIZE (4-386): 3.66e-51: 179: 14.46		K7TYT2_MAIZE (117-470): 6.03e-67: 223: 14.65
+	Hs
		198887 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		1020262 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		1020256 SAFB2_HUMAN (14-203): 1.29e-41: 158: 20.51		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		474019 PAB4L_HUMAN (31-303): 5.12e-41: 150: 14.59		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		1031344 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		1020249 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		1054335 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		1049456 SAFB2_HUMAN (14-203): 1.29e-41: 158: 20.51		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		1054620 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		1031328 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Mm
		665745 PABP1_MOUSE (22-296): 4e-35: 138: 15.55		TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70
+	Hs
		1031490 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50
+	Hs
		474021 PAB4L_HUMAN (31-303): 5.12e-41: 150: 14.59		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		516495 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		516339 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35