HitPredict

Interactor 1: RFOX2 (O43251)
RNA binding protein fox-1 homolog 2 (Fox-1 homolog B) (Hexaribonucleotide-binding protein 2) (RNA-binding motif protein 9) (RNA-binding protein 9) (Repressor of tamoxifen transcriptional activity)
Gene: RBFOX2

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 401
+	Mm
		857354 TIA1_MOUSE (116-302): 5.05e-26: 109: 19.17		SPF45_MOUSE (1-401): 3.28e-154: 442: 98.27
+	Hs
		198887 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054335 SAFB1_HUMAN (14-214): 5.77e-42: 159: 21.36		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1049456 SAFB2_HUMAN (14-203): 1.29e-41: 158: 20.51		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054620 RFOX1_HUMAN (19-390): 3.82e-40: 148: 59.46		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1031328 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		516518 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		198842 RFOX2_HUMAN (1-390): 1.43e-65: 215: 100.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Dm
		1370583 Q9VM49_DROME (87-202): 3.67e-33: 132: 33.06		Q9VM49_DROME (81-394): 1.42e-65: 220: 14.07
+	Hs
		1054309 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054407 RBM23_HUMAN (101-208): 1.46e-23: 103: 30.36		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		641756 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		516364 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1031490 PABP4_HUMAN (22-287): 1.65e-36: 142: 13.87		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		516730 PABP1_HUMAN (22-296): 2.88e-35: 138: 15.55		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Mm
		641996 TIA1_MOUSE (116-302): 5.05e-26: 109: 19.17		U2AF2_MOUSE (244-397): 2.5e-36: 140: 23.93
+	Hs
		641773 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1054653 RBM39_HUMAN (87-200): 4.21e-25: 108: 27.97		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67