HitPredict

Interactor 1: SPIT2 (O43291)
Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin)
Gene: SPINT2

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 252 Hs			1 499
+	Hs
		394195 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		AKT2_HUMAN (3-429): 1.86e-134: 399: 21.35
+	Hs
		394194 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		AKT1_HUMAN (3-428): 3.62e-133: 395: 20.59
+	Hs
		394562 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KPCE_HUMAN (8-428): 2.32e-128: 391: 17.05
+	Hs
		394075 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KAPCA_HUMAN (95-398): 1.19e-126: 374: 21.66
+	Hs
		518051 CO6A3_HUMAN (27-96): 1.01e-24: 104: 34.29		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		616703 APLP2_HUMAN (31-132): 9.41e-25: 104: 22.55		KS6B1_HUMAN (87-293): 8.22e-20: 94.4: 38.25
+	Hs
		394134 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		KS6B1_HUMAN (87-293): 8.22e-20: 94.4: 38.25
+	Hs
		394544 A4_HUMAN (136-184): 1.61e-20: 92.1: 55.10		CDK3_HUMAN (110-362): 3.53e-20: 92.8: 28.22