Protein: YTDC2
3'-5' RNA helicase YTHDC2 (EC 3.6.4.13) (YTH domain-containing protein 2) (hYTHDC2)

Gene: YTDC2, YTHDC2
Organism: Homo sapiens
Interactions: 204
UniProt ID: Q9H6S0

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0007286 - spermatid development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

323139

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

3

20

High-throughput

0.827

High

269881

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.691

High

281417

RL1D1
Ribosomal L1 domain-containing protein 1

1

5

High-throughput

0.691

High

922714

RL10A
Large ribosomal subunit protein uL1

1

5

High-throughput

0.691

High

944943

RED1
Double-stranded RNA-specific editase 1

1

19

High-throughput

0.691

High

962371

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

11

High-throughput

0.691

High

1019947

ILF3
Interleukin enhancer-binding factor 3

1

20

High-throughput

0.691

High

1332444

DDX21
Nucleolar RNA helicase 2

1

16

High-throughput

0.691

High

1332464

RL36
Large ribosomal subunit protein eL36

1

4

High-throughput

0.691

High

846869

SMCA2
Probable global transcription activator SNF2L2

1

13

High-throughput

0.665

High

908153

RS16
Small ribosomal subunit protein uS9

2

7

High-throughput

0.628

High

910571

RS14
Small ribosomal subunit protein uS11

2

3

High-throughput

0.628

High

971589

RL18A
Large ribosomal subunit protein eL20

2

2

High-throughput

0.628

High

1076107

OASL
2'-5'-oligoadenylate synthase-like protein

2

10

High-throughput

0.628

High

1326866

NXF2
Nuclear RNA export factor 2

2

2

High-throughput

0.628

High

1332449

NOP53
Ribosome biogenesis protein NOP53

2

3

High-throughput

0.628

High

942952

SRPK2
SRSF protein kinase 2

2

19

High-throughput

0.619

High

848482

IRAK1
Interleukin-1 receptor-associated kinase 1

2

0

High-throughput

0.618

High

1022210

NFX1
Transcriptional repressor NF-X1

1

10

High-throughput

0.618

High

171840

WDR46
WD repeat-containing protein 46

2

15

High-throughput

0.611

High

1116549

LARP7
La-related protein 7

2

20

High-throughput

0.611

High

1272613

CSN5
COP9 signalosome complex subunit 5

2

10

High-throughput

0.611

High

1239169

ZBT38
Zinc finger and BTB domain-containing protein 38

3

5

High-throughput

0.609

High

1332439

LN28A
Protein lin-28 homolog A

2

17

High-throughput

0.601

High

228705

PRKN
E3 ubiquitin-protein ligase parkin

2

20

High-throughput

0.584

High

603718

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

4

High-throughput

0.584

High

1332461

DICER
Endoribonuclease Dicer

1

18

Small-scale

0.575

High

513443

FGF3
Fibroblast growth factor 3

2

11

High-throughput

0.574

High

875572

FGF8
Fibroblast growth factor 8

2

11

High-throughput

0.574

High

1149629

Z324B
Zinc finger protein 324B

2

3

High-throughput

0.574

High

1188152

ZN550
Zinc finger protein 550

2

2

High-throughput

0.574

High

1297520

ZSC31
Zinc finger and SCAN domain-containing protein 31

2

5

High-throughput

0.574

High

1042544

CUL3
Cullin-3

2

20

High-throughput

0.558

High

1171725

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

1332455

HECD1
E3 ubiquitin-protein ligase HECTD1

1

18

High-throughput

0.553

High

1332457

FZR1
Fizzy-related protein homolog

1

19

High-throughput

0.553

High

71239

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

14

High-throughput

0.536

High

196193

RRP8
Ribosomal RNA-processing protein 8

1

1

High-throughput

0.536

High

236073

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.536

High

273254

SURF6
Surfeit locus protein 6

1

4

High-throughput

0.536

High

401109

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.536

High

489274

H14
Histone H1.4

1

17

High-throughput

0.536

High

515304

KPSH1
Serine/threonine-protein kinase H1

1

1

High-throughput

0.536

High

559248

H15
Histone H1.5

1

17

High-throughput

0.536

High

559946

H12
Histone H1.2

1

17

High-throughput

0.536

High

578133

RL17
Large ribosomal subunit protein uL22

1

4

High-throughput

0.536

High

616527

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.536

High

642599

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

736737

RL4
Large ribosomal subunit protein uL4

1

4

High-throughput

0.536

High

759830

RS19
Small ribosomal subunit protein eS19

1

4

High-throughput

0.536

High

773567

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

802226

NOP2
Probable 28S rRNA

1

3

High-throughput

0.536

High

806175

RL5
Large ribosomal subunit protein uL18

1

5

High-throughput

0.536

High

806684

RL28
Large ribosomal subunit protein eL28

1

1

High-throughput

0.536

High

807532

RS10
Small ribosomal subunit protein eS10

1

5

High-throughput

0.536

High

828903

SRP09
Signal recognition particle 9 kDa protein

1

4

High-throughput

0.536

High

842660

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.536

High

899355

RL15
Large ribosomal subunit protein eL15

1

3

High-throughput

0.536

High

913758

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.536

High

916379

RL23A
Large ribosomal subunit protein uL23

1

4

High-throughput

0.536

High

916866

RS6
Small ribosomal subunit protein eS6

1

5

High-throughput

0.536

High

922389

RL31
Large ribosomal subunit protein eL31

1

6

High-throughput

0.536

High

923526

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.536

High

945349

PRR3
Proline-rich protein 3

1

3

High-throughput

0.536

High

951763

RL19
Large ribosomal subunit protein eL19

1

5

High-throughput

0.536

High

972367

TIE2
Angiopoietin-1 receptor

1

4

High-throughput

0.536

High

1029095

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1039852

SNW1
SNW domain-containing protein 1

1

8

High-throughput

0.536

High

1052155

MAP7
Ensconsin

1

12

High-throughput

0.536

High

1073859

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

17

High-throughput

0.536

High

1150358

RL7L
Ribosomal protein uL30-like

1

2

High-throughput

0.536

High

1162458

CC137
Coiled-coil domain-containing protein 137

1

1

High-throughput

0.536

High

1263538

PSPC1
Paraspeckle component 1

1

20

High-throughput

0.536

High

1295955

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

1

High-throughput

0.536

High

1308769

RBM4B
RNA-binding protein 4B

1

9

High-throughput

0.536

High

1332447

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

6

High-throughput

0.536

High

1332452

PURG
Purine-rich element-binding protein gamma

1

4

High-throughput

0.536

High

1332454

ZN346
Zinc finger protein 346

1

7

High-throughput

0.536

High

1332456

ABT1
Activator of basal transcription 1

1

4

High-throughput

0.536

High

1332462

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

5

High-throughput

0.536

High

1332463

YBOX2
Y-box-binding protein 2

1

15

High-throughput

0.536

High

1332465

RBM19
Probable RNA-binding protein 19

1

15

High-throughput

0.536

High

1051463

DCTN1
Dynactin subunit 1

2

2

High-throughput

0.533

High

1148219

RNF43
E3 ubiquitin-protein ligase RNF43

2

1

High-throughput

0.533

High

370443

ESR1
Estrogen receptor

2

20

High-throughput

0.521

High

1206052

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.517

High

1310599

LLPH
Protein LLP homolog

1

0

High-throughput

0.513

High

180453

MAGB2
Melanoma-associated antigen B2

1

8

High-throughput

0.489

High

313631

TNF6B
Tumor necrosis factor receptor superfamily member 6B

1

3

High-throughput

0.489

High

316157

CBX6
Chromobox protein homolog 6

1

7

High-throughput

0.489

High

391905

H2A1B
Histone H2A type 1-B/E

1

13

High-throughput

0.489

High

470556

H2A1
Histone H2A type 1

1

13

High-throughput

0.489

High

485403

GLI4
Zinc finger protein GLI4

1

5

High-throughput

0.489

High

615477

KALM
Anosmin-1

1

1

High-throughput

0.489

High

781823

MNDA
Myeloid cell nuclear differentiation antigen

1

16

High-throughput

0.489

High

1054917

FGFP1
Fibroblast growth factor-binding protein 1

1

3

High-throughput

0.489

High

1069509

TEBP
Prostaglandin E synthase 3

1

5

High-throughput

0.489

High

1101006

RN151
RING finger protein 151

1

8

High-throughput

0.489

High

1169097

ZN574
Zinc finger protein 574

1

4

High-throughput

0.489

High

1190568

HEAT3
HEAT repeat-containing protein 3

1

2

High-throughput

0.489

High

1193044

ZN467
Zinc finger protein 467

1

2

High-throughput

0.489

High

1202119

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.489

High

1221462

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

3

High-throughput

0.489

High

1272773

FGF13
Fibroblast growth factor 13

1

11

High-throughput

0.489

High

1283586

TRI52
E3 ubiquitin-protein ligase TRIM52

1

7

High-throughput

0.489

High

1286811

ZN653
Zinc finger protein 653

1

3

High-throughput

0.489

High

1288629

PABP5
Polyadenylate-binding protein 5

1

9

High-throughput

0.489

High

1291194

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.489

High

1293115

ZN764
Zinc finger protein 764

1

4

High-throughput

0.489

High

1295842

ZN668
Zinc finger protein 668

1

3

High-throughput

0.489

High

1298273

ZNF48
Zinc finger protein 48

1

1

High-throughput

0.489

High

1302841

IMP2L
Mitochondrial inner membrane protease subunit 2

1

2

High-throughput

0.489

High

1332441

CBX8
Chromobox protein homolog 8

1

7

High-throughput

0.489

High

1332466

MB212
Protein mab-21-like 2

1

6

High-throughput

0.489

High

149292

CTRO
Citron Rho-interacting kinase

1

9

High-throughput

0.479

High

298797

UFL1
E3 UFM1-protein ligase 1

1

6

High-throughput

0.479

High

385526

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.479

High

432267

HS90A
Heat shock protein HSP 90-alpha

1

6

Small-scale

0.479

High

442495

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

20

High-throughput

0.479

High

455878

PARP1
Poly [ADP-ribose] polymerase 1

1

14

High-throughput

0.479

High

524004

XRCC6
X-ray repair cross-complementing protein 6

1

5

High-throughput

0.479

High

572683

VGFR1
Vascular endothelial growth factor receptor 1

1

7

High-throughput

0.479

High

652254

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

11

High-throughput

0.479

High

670647

ERP29
Endoplasmic reticulum resident protein 29

1

1

High-throughput

0.479

High

729358

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.479

High

738268

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

7

High-throughput

0.479

High

760318

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.479

High

780109

CCNF
Cyclin-F

1

7

High-throughput

0.479

High

835521

GSK3A
Glycogen synthase kinase-3 alpha

1

9

High-throughput

0.479

High

835994

GSK3B
Glycogen synthase kinase-3 beta

1

12

High-throughput

0.479

High

909124

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

12

High-throughput

0.479

High

969993

KIF23
Kinesin-like protein KIF23

1

11

High-throughput

0.479

High

1018054

GRSF1
G-rich sequence factor 1

1

20

High-throughput

0.479

High

1025964

TADBP
TAR DNA-binding protein 43

1

12

High-throughput

0.479

High

1029876

TIF1B
Transcription intermediary factor 1-beta

1

20

High-throughput

0.479

High

1066704

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1085955

IF16
Gamma-interferon-inducible protein 16

1

16

High-throughput

0.479

High

1128543

HABP4
Intracellular hyaluronan-binding protein 4

1

8

High-throughput

0.479

High

1136291

RC3H1
Roquin-1

1

11

High-throughput

0.479

High

1187779

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

14

High-throughput

0.479

High

1193178

SLN11
Schlafen family member 11

1

7

High-throughput

0.479

High

1201678

ZCH18
Zinc finger CCCH domain-containing protein 18

1

13

High-throughput

0.479

High

1224411

XRN1
5'-3' exoribonuclease 1

1

5

High-throughput

0.479

High

1236503

SIR6
NAD-dependent protein deacylase sirtuin-6

1

14

High-throughput

0.479

High

1237477

CGAS
Cyclic GMP-AMP synthase

1

6

High-throughput

0.479

High

1240992

SERB1
SERPINE1 mRNA-binding protein 1

1

8

High-throughput

0.479

High

1294006

DDRGK
DDRGK domain-containing protein 1

1

7

High-throughput

0.479

High

1306980

ANM1
Protein arginine N-methyltransferase 1

1

7

High-throughput

0.479

High

1316880

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

13

High-throughput

0.479

High

1327875

SIK2
Serine/threonine-protein kinase SIK2

1

3

Small-scale

0.479

High

1332440

RC3H2
Roquin-2

1

13

High-throughput

0.479

High

1332448

LYAR
Cell growth-regulating nucleolar protein

1

3

High-throughput

0.479

High

1332450

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

10

High-throughput

0.479

High

1332460

RL26L
Ribosomal protein uL24-like

1

5

High-throughput

0.479

High

1332438

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

9

High-throughput

0.470

High

1332458

MYO6
Unconventional myosin-VI

1

0

Small-scale

0.458

High

890843

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

4

High-throughput

0.457

High

1332446

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

387522

P53
Cellular tumor antigen p53

1

8

Small-scale

0.445

High

402478

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

989125

FMR1
Fragile X messenger ribonucleoprotein 1

1

6

High-throughput

0.445

High

1130593

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.445

High

1328031

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

18

High-throughput

0.445

High

125714

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

High-throughput

0.437

High

164480

TRI66
Tripartite motif-containing protein 66

1

20

High-throughput

0.437

High

170477

TIF1A
Transcription intermediary factor 1-alpha

1

20

Small-scale

0.437

High

303486

HEXI1
Protein HEXIM1

1

5

High-throughput

0.437

High

347898

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.437

High

379866

MYCN
N-myc proto-oncogene protein

1

17

High-throughput

0.437

High

553716

RFA2
Replication protein A 32 kDa subunit

1

14

High-throughput

0.437

High

721450

RFA3
Replication protein A 14 kDa subunit

1

12

High-throughput

0.437

High

818469

SOX2
Transcription factor SOX-2

1

12

High-throughput

0.437

High

1034997

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

6

High-throughput

0.437

High

1053658

GRM2
Metabotropic glutamate receptor 2

1

3

High-throughput

0.437

High

1146839

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.437

High

1188866

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

11

High-throughput

0.437

High

1200669

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.437

High

1232132

RHG18
Rho GTPase-activating protein 18

1

2

High-throughput

0.437

High

1239326

KDF1
Keratinocyte differentiation factor 1

1

4

High-throughput

0.437

High

1243940

FBX22
F-box only protein 22

1

1

High-throughput

0.437

High

1260911

DCAF4
DDB1- and CUL4-associated factor 4

1

3

High-throughput

0.437

High

1266556

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.437

High

1269620

ESR2
Estrogen receptor beta

1

20

High-throughput

0.437

High

1300943

CIC
Protein capicua homolog

1

14

High-throughput

0.437

High

1328249

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.437

High

1331289

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

1332442

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.437

High

1332443

ANLN
Anillin

1

7

High-throughput

0.437

High

1332445

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

14

High-throughput

0.437

High

1332453

FBW1B
F-box/WD repeat-containing protein 11

1

13

High-throughput

0.437

High

1332459

CC14A
Dual specificity protein phosphatase CDC14A

1

6

High-throughput

0.437

High

1332467

MAFB
Transcription factor MafB

1

14

High-throughput

0.437

High

170719

AXIN1
Axin-1

1

0

Small-scale

0.426

High

69621

B0UZZ8
Chromosome 6 open reading frame 11

1

15

High-throughput

0.407

High

306321

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

18

High-throughput

0.407

High

1082157

CRY1
Cryptochrome-1

1

2

Small-scale

0.407

High

1318849

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.407

High

1297785

ZN512
Zinc finger protein 512

2

0

High-throughput

0.328

High

1071074

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.306

High

451561

CLCA
Clathrin light chain A

1

0

High-throughput

0.279

Low

799442

TNNT3
Troponin T, fast skeletal muscle

1

0

High-throughput

0.279

Low

885698

NXPH1
Neurexophilin-1

1

0

High-throughput

0.279

Low

1203536

TEN1L
CST complex subunit TEN1

1

0

High-throughput

0.279

Low

1332451

C2D2A
Coiled-coil and C2 domain-containing protein 2A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024