HitPredict

Interactor 1: DAPK3 (O43293)
Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (Zipper-interacting protein kinase) (ZIP-kinase)
Gene: DAPK3

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FHA~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1584
+	Hs
		1039082 KCC2D_HUMAN (2-350): 4.78e-128: 381: 31.77		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		295807 ST17B_HUMAN (5-276): 4.72e-80: 254: 47.10		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1131875 ST17A_HUMAN (2-275): 8.85e-75: 241: 44.80		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		1083214 KCC4_HUMAN (6-298): 8.21e-63: 212: 40.60		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		200133 DAPK3_HUMAN (1-454): 2.66e-158: 457: 100.00		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		862028 DAPK1_HUMAN (1-279): 3.41e-134: 421: 81.36		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Ce
		136802 UNC22_CAEEL (5-327): 7.69e-70: 243: 38.30		UNC89_CAEEL (105-1371): 2.34e-27: 124: 9.91
+	Dm
		54892 A1ZA72_DROME (8-319): 1.38e-60: 216: 38.68		Q9VLS7_DROME (601-1577): 6.1e-21: 102: 7.84
+	Mm
		57869 KALRN_MOUSE (6-276): 3.74e-62: 220: 40.59		ANK2_MOUSE (123-1379): 8.94e-11: 69.4: 13.83