Protein: SIR1
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 2.3.1.286) (NAD-dependent protein deacylase sirtuin-1) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)]

Gene: SIR1, SIRT1
Organism: Homo sapiens
Interactions: 403
UniProt ID: Q96EB6

Gene Ontology (top 5):
GO:0000012 - single strand break repair
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000183 - rDNA heterochromatin formation
GO:0000720 - pyrimidine dimer repair by nucleotide-excision repair
GO:0000731 - DNA synthesis involved in DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1289395

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

11

Small-scale

0.768

High

387278

P53
Cellular tumor antigen p53

15

5

Small-scale

0.766

High

1230509

CCAR2
Cell cycle and apoptosis regulator protein 2

9

5

Small-scale

0.759

High

1289478

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

11

2

Small-scale

0.753

High

1029723

TIF1B
Transcription intermediary factor 1-beta

5

4

Small-scale

0.719

High

402338

JUN
Transcription factor Jun

5

5

Small-scale

0.714

High

934385

CSK21
Casein kinase II subunit alpha

5

8

Small-scale

0.712

High

1016228

FOXO1
Forkhead box protein O1

5

13

Small-scale

0.706

High

206850

FOXO3
Forkhead box protein O3

4

13

Small-scale

0.704

High

234667

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

6

0

Small-scale

0.700

High

978849

TF65
Transcription factor p65

4

7

Small-scale

0.700

High

960144

CDKL1
Cyclin-dependent kinase-like 1

4

6

High-throughput

0.699

High

1031924

MTA1
Metastasis-associated protein MTA1

4

3

Small-scale

0.694

High

998968

EP300
Histone acetyltransferase p300

4

13

Small-scale

0.691

High

1203665

AROS
Active regulator of SIRT1

5

0

Small-scale

0.689

High

641262

DNMT1
DNA

3

8

Small-scale

0.686

High

1055104

HIC1
Hypermethylated in cancer 1 protein

4

6

Small-scale

0.683

High

1080224

EZH2
Histone-lysine N-methyltransferase EZH2

3

12

Small-scale

0.678

High

741079

ZEB1
Zinc finger E-box-binding homeobox 1

4

6

Small-scale

0.676

High

181663

FGF10
Fibroblast growth factor 10

3

3

High-throughput

0.667

High

447279

HXB5
Homeobox protein Hox-B5

3

9

High-throughput

0.667

High

550893

RS2
Small ribosomal subunit protein uS5

3

2

High-throughput

0.667

High

1198570

TAD2B
Transcriptional adapter 2-beta

3

5

High-throughput

0.667

High

1239146

ZBT38
Zinc finger and BTB domain-containing protein 38

3

2

High-throughput

0.667

High

1289460

CWC15
Spliceosome-associated protein CWC15 homolog

3

1

High-throughput

0.667

High

1273431

KAT5
Histone acetyltransferase KAT5

3

5

Small-scale

0.664

High

262537

TULP3
Tubby-related protein 3

4

0

Small-scale

0.664

High

1050617

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

2

7

Small-scale

0.659

High

738988

SRBP1
Sterol regulatory element-binding protein 1

2

6

Small-scale

0.656

High

1271483

KAT2B
Histone acetyltransferase KAT2B

2

15

Small-scale

0.655

High

347555

MYC
Myc proto-oncogene protein

2

7

Small-scale

0.653

High

963663

E2F1
Transcription factor E2F1

3

0

Small-scale

0.649

High

931787

CSK2B
Casein kinase II subunit beta

2

3

Small-scale

0.644

High

311740

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

2

1

Small-scale

0.641

High

1289481

IRS2
Insulin receptor substrate 2

2

8

Small-scale

0.641

High

295115

RECQ4
ATP-dependent DNA helicase Q4

3

9

Small-scale

0.640

High

1289440

ECT2
Protein ECT2

3

3

Small-scale

0.640

High

415021

CDK1
Cyclin-dependent kinase 1

2

6

Small-scale

0.639

High

787541

MTOR
Serine/threonine-protein kinase mTOR

2

10

Small-scale

0.639

High

850870

AK1D1
Aldo-keto reductase family 1 member D1

3

0

High-throughput

0.638

High

1151038

SFRP4
Secreted frizzled-related protein 4

3

0

High-throughput

0.638

High

203758

SUV91
Histone-lysine N-methyltransferase SUV39H1

2

4

Small-scale

0.634

High

455752

PARP1
Poly [ADP-ribose] polymerase 1

2

6

Small-scale

0.634

High

497426

TAU
Microtubule-associated protein tau

2

5

Small-scale

0.634

High

1289438

KAT8
Histone acetyltransferase KAT8

2

5

Small-scale

0.634

High

66689

ZN785
Zinc finger protein 785

2

6

High-throughput

0.628

High

834098

CLK3
Dual specificity protein kinase CLK3

2

11

High-throughput

0.628

High

1188145

ZN550
Zinc finger protein 550

2

4

High-throughput

0.628

High

1205169

Z354C
Zinc finger protein 354C

2

2

High-throughput

0.628

High

1285880

ZN669
Zinc finger protein 669

2

3

High-throughput

0.628

High

1289441

WDR76
WD repeat-containing protein 76

2

7

High-throughput

0.628

High

1289465

APEX2
DNA-(apurinic or apyrimidinic site) endonuclease 2

2

2

High-throughput

0.628

High

261564

NCOR1
Nuclear receptor corepressor 1

2

8

Small-scale

0.624

High

523930

XRCC6
X-ray repair cross-complementing protein 6

2

5

Small-scale

0.624

High

1085639

HIF1A
Hypoxia-inducible factor 1-alpha

2

10

Small-scale

0.624

High

1289443

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

6

Small-scale

0.624

High

568223

TAL1
T-cell acute lymphocytic leukemia protein 1

2

5

High-throughput

0.618

High

1220757

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

11

Small-scale

0.618

High

1289450

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

11

Small-scale

0.618

High

510032

ERR1
Steroid hormone receptor ERR1

2

15

Small-scale

0.611

High

268219

EED
Polycomb protein EED

2

4

Small-scale

0.611

High

432145

HS90A
Heat shock protein HSP 90-alpha

2

3

Small-scale

0.611

High

538587

CCNB1
G2/mitotic-specific cyclin-B1

2

3

Small-scale

0.611

High

941944

PITX1
Pituitary homeobox 1

2

5

High-throughput

0.611

High

973173

RL6
Large ribosomal subunit protein eL6

2

1

High-throughput

0.611

High

1272798

FGF11
Fibroblast growth factor 11

2

3

High-throughput

0.611

High

1289444

SP110
Sp110 nuclear body protein

2

12

High-throughput

0.611

High

740580

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.604

High

161862

ZN263
Zinc finger protein 263

2

0

High-throughput

0.602

High

1115862

CERKL
Ceramide kinase-like protein

2

0

High-throughput

0.602

High

1229656

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.602

High

1289411

SOST
Sclerostin

2

0

High-throughput

0.602

High

1289456

TBCC1
TBCC domain-containing protein 1

2

0

High-throughput

0.602

High

565130

ZNF8
Zinc finger protein 8

2

6

High-throughput

0.601

High

724560

IRS1
Insulin receptor substrate 1

2

9

Small-scale

0.601

High

880800

HDAC4
Histone deacetylase 4

2

10

Small-scale

0.601

High

1270371

HDAC2
Histone deacetylase 2

2

9

Small-scale

0.601

High

1079128

STK11
Serine/threonine-protein kinase STK11

2

0

Small-scale

0.598

High

175907

P73
Tumor protein p73

1

5

Small-scale

0.596

High

652954

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

Small-scale

0.596

High

681976

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.596

High

1119411

VWA3B
von Willebrand factor A domain-containing protein 3B

2

0

High-throughput

0.595

High

1163790

RICTR
Rapamycin-insensitive companion of mTOR

2

2

Small-scale

0.595

High

1039764

SNW1
SNW domain-containing protein 1

1

2

Small-scale

0.594

High

668899

PML
Protein PML

1

8

Small-scale

0.589

High

1074312

NR0B2
Nuclear receptor subfamily 0 group B member 2

1

14

Small-scale

0.589

High

1259474

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

Small-scale

0.589

High

488009

RARA
Retinoic acid receptor alpha

1

20

Small-scale

0.586

High

1063547

SUZ12
Polycomb protein SUZ12

2

0

Small-scale

0.585

High

244768

BRD4
Bromodomain-containing protein 4

2

13

Small-scale

0.584

High

370178

ESR1
Estrogen receptor

2

20

Small-scale

0.584

High

418539

NPM
Nucleophosmin

2

2

Small-scale

0.584

High

782624

HNF4A
Hepatocyte nuclear factor 4-alpha

2

15

Small-scale

0.584

High

1038619

HDAC1
Histone deacetylase 1

2

9

Small-scale

0.584

High

1271439

KAT2A
Histone acetyltransferase KAT2A

2

15

Small-scale

0.584

High

246260

NBN
Nibrin

1

0

Small-scale

0.583

High

345519

FOS
Protein c-Fos

1

4

Small-scale

0.578

High

379705

MYCN
N-myc proto-oncogene protein

1

8

Small-scale

0.578

High

487663

ANDR
Androgen receptor

1

14

Small-scale

0.578

High

958171

FOXO4
Forkhead box protein O4

1

12

Small-scale

0.578

High

1052283

SRC8
Src substrate cortactin

1

2

Small-scale

0.578

High

1054243

HES1
Transcription factor HES-1

1

5

Small-scale

0.578

High

1289396

CHFR
E3 ubiquitin-protein ligase CHFR

1

1

Small-scale

0.578

High

1289433

HIPK2
Homeodomain-interacting protein kinase 2

1

16

Small-scale

0.578

High

1289464

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

5

Small-scale

0.578

High

1289466

BAZ1B
Tyrosine-protein kinase BAZ1B

1

20

Small-scale

0.578

High

1289462

DNM3B
DNA

2

0

Small-scale

0.576

High

980636

TLE1
Transducin-like enhancer protein 1

1

2

Small-scale

0.573

High

1080751

ZYX
Zyxin

1

2

Small-scale

0.573

High

414354

RB
Retinoblastoma-associated protein

2

0

Small-scale

0.569

High

960228

CDK6
Cyclin-dependent kinase 6

1

7

Small-scale

0.569

High

1289442

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

1

0

Small-scale

0.564

High

126159

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

13

Small-scale

0.561

High

167382

SMAD7
Mothers against decapentaplegic homolog 7

1

1

Small-scale

0.561

High

181552

CLOCK
Circadian locomoter output cycles protein kaput

1

10

Small-scale

0.561

High

382104

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

3

Small-scale

0.561

High

509971

VDR
Vitamin D3 receptor

1

18

Small-scale

0.561

High

567872

HXB9
Homeobox protein Hox-B9

1

7

Small-scale

0.561

High

595948

HNF1A
Hepatocyte nuclear factor 1-alpha

1

6

Small-scale

0.561

High

625550

CDK2
Cyclin-dependent kinase 2

1

6

Small-scale

0.561

High

651929

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

Small-scale

0.561

High

800818

MK08
Mitogen-activated protein kinase 8

1

4

Small-scale

0.561

High

898996

PSME3
Proteasome activator complex subunit 3

1

1

Small-scale

0.561

High

962914

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

Small-scale

0.561

High

992439

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.561

High

993338

FOXM1
Forkhead box protein M1

1

3

Small-scale

0.561

High

1043511

CUL4B
Cullin-4B

1

5

Small-scale

0.561

High

1082329

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.561

High

1289404

MPP8
M-phase phosphoprotein 8

1

9

Small-scale

0.561

High

1289406

NECD
Necdin

1

3

Small-scale

0.561

High

1289409

EPAS1
Endothelial PAS domain-containing protein 1

1

8

Small-scale

0.561

High

1289410

ANM1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.561

High

1289421

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

5

Small-scale

0.561

High

1289429

BC11A
B-cell lymphoma/leukemia 11A

1

5

Small-scale

0.561

High

1289463

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

1

Small-scale

0.561

High

776784

STAT3
Signal transducer and activator of transcription 3

2

0

Small-scale

0.559

High

1256325

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

2

0

Small-scale

0.559

High

1289403

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.554

High

612494

XPA
DNA repair protein complementing XP-A cells

1

0

Small-scale

0.554

High

1024071

ACACA
Acetyl-CoA carboxylase 1

1

16

Small-scale

0.546

High

363980

FETA
Alpha-fetoprotein

1

0

Small-scale

0.537

High

966989

SATB1
DNA-binding protein SATB1

1

0

Small-scale

0.537

High

1200109

CATAC
Centrosomal AT-AC splicing factor

1

0

Small-scale

0.537

High

1289401

NR1H4
Bile acid receptor

1

20

Small-scale

0.536

High

49255

FEZF1
Fez family zinc finger protein 1

1

3

High-throughput

0.536

High

199803

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

5

Small-scale

0.536

High

470123

H2AZ
Histone H2A.Z

1

10

High-throughput

0.536

High

586914

CSK22
Casein kinase II subunit alpha'

1

8

Small-scale

0.536

High

595620

HXA5
Homeobox protein Hox-A5

1

8

High-throughput

0.536

High

702124

RL9
Large ribosomal subunit protein uL6

1

2

High-throughput

0.536

High

789919

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.536

High

899661

FGF12
Fibroblast growth factor 12

1

3

High-throughput

0.536

High

913679

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.536

High

985244

HME1
Homeobox protein engrailed-1

1

7

High-throughput

0.536

High

1018634

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

13

Small-scale

0.536

High

1055967

ZN460
Zinc finger protein 460

1

2

High-throughput

0.536

High

1104166

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

4

High-throughput

0.536

High

1153042

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

2

High-throughput

0.536

High

1230014

RPTOR
Regulatory-associated protein of mTOR

1

4

Small-scale

0.536

High

1230642

SIX5
Homeobox protein SIX5

1

3

High-throughput

0.536

High

1254431

ZN675
Zinc finger protein 675

1

2

High-throughput

0.536

High

1259604

THAP3
THAP domain-containing protein 3

1

1

High-throughput

0.536

High

1264040

MYO3B
Myosin-IIIb

1

7

High-throughput

0.536

High

1272759

FGF13
Fibroblast growth factor 13

1

3

High-throughput

0.536

High

1286300

ZN707
Zinc finger protein 707

1

4

High-throughput

0.536

High

1289397

ZN514
Zinc finger protein 514

1

4

High-throughput

0.536

High

1289398

ZMAT2
Zinc finger matrin-type protein 2

1

2

High-throughput

0.536

High

1289414

NOC4L
Nucleolar complex protein 4 homolog

1

5

Small-scale

0.536

High

1289439

DCR1B
5' exonuclease Apollo

1

2

High-throughput

0.536

High

1289447

AGO4
Protein argonaute-4

1

2

High-throughput

0.536

High

1289459

DDX56
Probable ATP-dependent RNA helicase DDX56

1

9

High-throughput

0.536

High

1289476

ZN777
Zinc finger protein 777

1

3

High-throughput

0.536

High

150745

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

7

Small-scale

0.534

High

196156

RRP8
Ribosomal RNA-processing protein 8

1

2

Small-scale

0.534

High

131488

IMA4
Importin subunit alpha-4

1

7

Small-scale

0.515

High

131661

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

13

Small-scale

0.515

High

151132

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

6

Small-scale

0.515

High

500006

CH60
60 kDa heat shock protein, mitochondrial

1

5

Small-scale

0.515

High

502423

BIP
Endoplasmic reticulum chaperone BiP

1

10

Small-scale

0.515

High

644125

EF1G
Elongation factor 1-gamma

1

1

Small-scale

0.515

High

655441

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

Small-scale

0.515

High

667717

NOS3
Nitric oxide synthase 3

1

1

Small-scale

0.515

High

702502

C2TA
MHC class II transactivator

1

3

Small-scale

0.515

High

714048

HS71L
Heat shock 70 kDa protein 1-like

1

6

Small-scale

0.515

High

717275

CTNB1
Catenin beta-1

1

11

Small-scale

0.515

High

853420

IMA1
Importin subunit alpha-1

1

7

Small-scale

0.515

High

918599

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

Small-scale

0.515

High

974646

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

Small-scale

0.515

High

1051641

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

1

Small-scale

0.515

High

1077447

ELAV1
ELAV-like protein 1

1

3

Small-scale

0.515

High

1205889

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

1

4

Small-scale

0.515

High

1216244

H2A2B
Histone H2A type 2-B

1

9

Small-scale

0.515

High

1273601

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

7

Small-scale

0.515

High

1289424

NAT10
RNA cytidine acetyltransferase

1

2

Small-scale

0.515

High

1289432

ATG5
Autophagy protein 5

1

1

Small-scale

0.515

High

1289445

ELL3
RNA polymerase II elongation factor ELL3

1

2

Small-scale

0.515

High

1289482

HES2
Transcription factor HES-2

1

7

Small-scale

0.515

High

664315

IMPA1
Inositol monophosphatase 1

1

0

High-throughput

0.513

High

822809

TNNI2
Troponin I, fast skeletal muscle

1

0

High-throughput

0.513

High

824661

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

958500

CYC
Cytochrome c

1

0

High-throughput

0.513

High

985466

STP2
Nuclear transition protein 2

1

0

High-throughput

0.513

High

1045269

THOC5
THO complex subunit 5 homolog

1

0

High-throughput

0.513

High

1289436

RPP21
Ribonuclease P protein subunit p21

1

0

High-throughput

0.513

High

1289467

TRM6
tRNA

1

0

High-throughput

0.513

High

1289480

FBX7
F-box only protein 7

1

0

High-throughput

0.513

High

975305

KMT2A
Histone-lysine N-methyltransferase 2A

1

10

Small-scale

0.506

High

930346

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.501

High

935101

H31
Histone H3.1

1

10

Small-scale

0.501

High

992186

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

2

Small-scale

0.501

High

1023091

STK4
Serine/threonine-protein kinase 4

1

2

Small-scale

0.501

High

1289420

BHE41
Class E basic helix-loop-helix protein 41

1

7

Small-scale

0.501

High

855993

ZN138
Zinc finger protein 138

1

3

High-throughput

0.500

High

1168889

ZN793
Zinc finger protein 793

1

3

High-throughput

0.500

High

1039535

ITPK1
Inositol-tetrakisphosphate 1-kinase

1

0

Small-scale

0.494

High

835098

TSC2
Tuberin

1

0

Small-scale

0.493

High

931330

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.493

High

1047206

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

Small-scale

0.493

High

1119959

RHG29
Rho GTPase-activating protein 29

1

0

Small-scale

0.493

High

1159598

MTFR2
Mitochondrial fission regulator 2

1

0

High-throughput

0.493

High

1289451

ZHANG
CREB/ATF bZIP transcription factor

1

0

Small-scale

0.493

High

1289453

DIAP3
Protein diaphanous homolog 3

1

0

Small-scale

0.493

High

1289486

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

0

Small-scale

0.493

High

1167889

DJC14
DnaJ homolog subfamily C member 14

1

2

High-throughput

0.489

High

902712

SUMO2
Small ubiquitin-related modifier 2

1

0

Small-scale

0.480

High

1079573

NEDD8
NEDD8

1

0

Small-scale

0.480

High

1289416

FANCJ
Fanconi anemia group J protein

1

0

Small-scale

0.480

High

56549

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

4

High-throughput

0.479

High

116614

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

3

High-throughput

0.479

High

125639

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

6

Small-scale

0.479

High

213903

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

11

Small-scale

0.479

High

215011

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

1

Small-scale

0.479

High

215154

LANC1
Glutathione S-transferase LANCL1

1

1

Small-scale

0.479

High

228325

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

236007

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

4

Small-scale

0.479

High

238722

IMA7
Importin subunit alpha-7

1

7

High-throughput

0.479

High

238812

UGDH
UDP-glucose 6-dehydrogenase

1

2

Small-scale

0.479

High

278852

DNJC8
DnaJ homolog subfamily C member 8

1

5

High-throughput

0.479

High

279334

DNJB5
DnaJ homolog subfamily B member 5

1

1

High-throughput

0.479

High

296099

MTA2
Metastasis-associated protein MTA2

1

3

Small-scale

0.479

High

312082

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

9

Small-scale

0.479

High

314673

PARN
Poly(A)-specific ribonuclease PARN

1

1

High-throughput

0.479

High

319299

BRD1
Bromodomain-containing protein 1

1

4

High-throughput

0.479

High

319964

HERC2
E3 ubiquitin-protein ligase HERC2

1

11

Small-scale

0.479

High

331323

CHK2
Serine/threonine-protein kinase Chk2

1

5

Small-scale

0.479

High

360260

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

Small-scale

0.479

High

449792

HMGB1
High mobility group protein B1

1

6

Small-scale

0.479

High

450575

RET1
Retinol-binding protein 1

1

1

Small-scale

0.479

High

561656

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

3

Small-scale

0.479

High

568104

JUND
Transcription factor JunD

1

4

Small-scale

0.479

High

608289

KCNA5
Potassium voltage-gated channel subfamily A member 5

1

1

Small-scale

0.479

High

616849

JAK1
Tyrosine-protein kinase JAK1

1

1

Small-scale

0.479

High

663988

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

2

High-throughput

0.479

High

670997

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

2

Small-scale

0.479

High

714355

HSP74
Heat shock 70 kDa protein 4

1

13

Small-scale

0.479

High

718091

BMI1
Polycomb complex protein BMI-1

1

3

Small-scale

0.479

High

750406

COIL
Coilin

1

1

High-throughput

0.479

High

751761

GRP75
Stress-70 protein, mitochondrial

1

14

Small-scale

0.479

High

781413

BCL6
B-cell lymphoma 6 protein

1

4

Small-scale

0.479

High

788057

AF9
Protein AF-9

1

3

Small-scale

0.479

High

808837

YAP1
Transcriptional coactivator YAP1

1

6

Small-scale

0.479

High

831574

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

843555

PAPOA
Poly(A) polymerase alpha

1

1

Small-scale

0.479

High

848269

HCFC1
Host cell factor 1

1

4

Small-scale

0.479

High

874391

NR1H2
Oxysterols receptor LXR-beta

1

20

Small-scale

0.479

High

885178

FOXL2
Forkhead box protein L2

1

3

Small-scale

0.479

High

896514

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

Small-scale

0.479

High

904080

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

7

Small-scale

0.479

High

940730

NOP14
Nucleolar protein 14

1

1

Small-scale

0.479

High

952539

H33
Histone H3.3

1

10

High-throughput

0.479

High

959592

VIGLN
Vigilin

1

6

High-throughput

0.479

High

961236

HSF1
Heat shock factor protein 1

1

1

Small-scale

0.479

High

964517

RELB
Transcription factor RelB

1

7

Small-scale

0.479

High

967343

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

971837

HEN2
Helix-loop-helix protein 2

1

5

Small-scale

0.479

High

974508

ENL
Protein ENL

1

7

Small-scale

0.479

High

997850

RBBP4
Histone-binding protein RBBP4

1

7

Small-scale

0.479

High

1025265

NR1H3
Oxysterols receptor LXR-alpha

1

20

Small-scale

0.479

High

1027179

CBX3
Chromobox protein homolog 3

1

6

High-throughput

0.479

High

1030914

KCAB2
Voltage-gated potassium channel subunit beta-2

1

1

Small-scale

0.479

High

1036457

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

2

Small-scale

0.479

High

1042252

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1043158

CUL4A
Cullin-4A

1

5

Small-scale

0.479

High

1044039

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

14

Small-scale

0.479

High

1050747

FHL2
Four and a half LIM domains protein 2

1

2

Small-scale

0.479

High

1065982

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

1

Small-scale

0.479

High

1083343

RBBP7
Histone-binding protein RBBP7

1

7

Small-scale

0.479

High

1084138

OCLN
Occludin

1

2

High-throughput

0.479

High

1086154

DUS5
Dual specificity protein phosphatase 5

1

1

High-throughput

0.479

High

1117682

ARI4B
AT-rich interactive domain-containing protein 4B

1

9

Small-scale

0.479

High

1139855

OBI1
ORC ubiquitin ligase 1

1

1

Small-scale

0.479

High

1140445

K2C79
Keratin, type II cytoskeletal 79

1

3

Small-scale

0.479

High

1151029

Q6FHH6
Glutathione S-transferase LANCL1

1

1

Small-scale

0.479

High

1155867

PHLB3
Pleckstrin homology-like domain family B member 3

1

6

Small-scale

0.479

High

1158794

TAF2
Transcription initiation factor TFIID subunit 2

1

2

Small-scale

0.479

High

1171186

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1173948

UBP31
Ubiquitin carboxyl-terminal hydrolase 31

1

6

Small-scale

0.479

High

1198265

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

6

Small-scale

0.479

High

1198494

Q86TH3
Dishevelled, dsh homolog 1

1

4

Small-scale

0.479

High

1198649

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

3

Small-scale

0.479

High

1222513

SLX4
Structure-specific endonuclease subunit SLX4

1

7

High-throughput

0.479

High

1230754

Q8N1C8
Stress-70 protein, mitochondrial

1

14

Small-scale

0.479

High

1232420

CMYA5
Cardiomyopathy-associated protein 5

1

8

Small-scale

0.479

High

1246141

COP1
E3 ubiquitin-protein ligase COP1

1

8

Small-scale

0.479

High

1264160

DNJC9
DnaJ homolog subfamily C member 9

1

5

High-throughput

0.479

High

1266875

TOPB1
DNA topoisomerase 2-binding protein 1

1

4

Small-scale

0.479

High

1270867

KAT6A
Histone acetyltransferase KAT6A

1

14

High-throughput

0.479

High

1273784

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

13

Small-scale

0.479

High

1281302

FBXW7
F-box/WD repeat-containing protein 7

1

5

Small-scale

0.479

High

1282695

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

9

High-throughput

0.479

High

1289328

SPDLY
Protein Spindly

1

5

Small-scale

0.479

High

1289402

TRIB3
Tribbles homolog 3

1

3

Small-scale

0.479

High

1289405

POP1
Ribonucleases P/MRP protein subunit POP1

1

2

High-throughput

0.479

High

1289407

PITX2
Pituitary homeobox 2

1

5

High-throughput

0.479

High

1289417

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

6

High-throughput

0.479

High

1289418

FOXP3
Forkhead box protein P3

1

7

Small-scale

0.479

High

1289422

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

2

High-throughput

0.479

High

1289423

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

1289425

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

6

Small-scale

0.479

High

1289426

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

5

Small-scale

0.479

High

1289427

TSYL1
Testis-specific Y-encoded-like protein 1

1

3

Small-scale

0.479

High

1289428

ING2
Inhibitor of growth protein 2

1

8

Small-scale

0.479

High

1289430

DUS15
Dual specificity protein phosphatase 15

1

1

High-throughput

0.479

High

1289435

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

5

Small-scale

0.479

High

1289446

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

6

Small-scale

0.479

High

1289449

Q9NQ82
Uridine diphospho-glucose dehydrogenase

1

2

Small-scale

0.479

High

1289455

DJC17
DnaJ homolog subfamily C member 17

1

10

High-throughput

0.479

High

1289457

WDR70
WD repeat-containing protein 70

1

2

Small-scale

0.479

High

1289468

ING1
Inhibitor of growth protein 1

1

8

Small-scale

0.479

High

1289469

DJC12
DnaJ homolog subfamily C member 12

1

6

High-throughput

0.479

High

1289471

AGO2
Protein argonaute-2

1

2

High-throughput

0.479

High

1289472

NUP50
Nuclear pore complex protein Nup50

1

4

High-throughput

0.479

High

1289474

ZN346
Zinc finger protein 346

1

2

Small-scale

0.479

High

1289477

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

3

Small-scale

0.479

High

1289484

MAFB
Transcription factor MafB

1

4

High-throughput

0.479

High

1289485

HCFC2
Host cell factor 2

1

4

Small-scale

0.479

High

265239

SAP30
Histone deacetylase complex subunit SAP30

1

0

Small-scale

0.458

High

297926

ST65G
STAGA complex 65 subunit gamma

1

0

Small-scale

0.458

High

328631

MBD3
Methyl-CpG-binding domain protein 3

1

0

Small-scale

0.458

High

352683

TNFA
Tumor necrosis factor

1

0

Small-scale

0.458

High

521291

SKI
Ski oncogene

1

0

Small-scale

0.458

High

556943

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

579725

XRCC1
DNA repair protein XRCC1

1

0

Small-scale

0.458

High

673615

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

686030

ARRB2
Beta-arrestin-2

1

0

Small-scale

0.458

High

772107

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

792244

MTHR
Methylenetetrahydrofolate reductase

1

0

High-throughput

0.458

High

820363

SPB4
Serpin B4

1

0

Small-scale

0.458

High

919665

RAP1A
Ras-related protein Rap-1A

1

0

Small-scale

0.458

High

921384

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

1062109

AT7L3
Ataxin-7-like protein 3

1

0

Small-scale

0.458

High

1103591

UVSSA
UV-stimulated scaffold protein A

1

0

Small-scale

0.458

High

1121380

AKIR2
Akirin-2

1

0

Small-scale

0.458

High

1156848

R13P3
Putative ribosomal protein uL13-like

1

0

High-throughput

0.458

High

1218400

MFN1
Mitofusin-1

1

0

Small-scale

0.458

High

1260864

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1266644

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1284923

ARK2N
Protein ARK2N

1

0

High-throughput

0.458

High

1285726

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1289399

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1289400

PUS7
Pseudouridylate synthase 7 homolog

1

0

Small-scale

0.458

High

1289408

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

0

Small-scale

0.458

High

1289415

SCNM1
Sodium channel modifier 1

1

0

Small-scale

0.458

High

1289419

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1289434

MTRFR
Mitochondrial translation release factor in rescue

1

0

High-throughput

0.458

High

1289437

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1289448

AKIP1
A-kinase-interacting protein 1

1

0

Small-scale

0.458

High

1289452

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.458

High

1289458

BCD1
Box C/D snoRNA protein 1

1

0

Small-scale

0.458

High

1289470

TNIK
TRAF2 and NCK-interacting protein kinase

1

2

High-throughput

0.457

High

57947

ZN320
Zinc finger protein 320

1

5

High-throughput

0.445

High

64145

ZN729
Zinc finger protein 729

1

1

High-throughput

0.445

High

73081

ZN736
Zinc finger protein 736

1

2

High-throughput

0.445

High

563422

ZNF20
Zinc finger protein 20

1

3

High-throughput

0.445

High

587674

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

13

Small-scale

0.445

High

837061

MRE11
Double-strand break repair protein MRE11

1

2

Small-scale

0.445

High

970665

ZNF45
Zinc finger protein 45

1

1

High-throughput

0.445

High

1158945

ZFP1
Zinc finger protein 1 homolog

1

2

High-throughput

0.445

High

1184443

ZN765
Zinc finger protein 765

1

4

High-throughput

0.445

High

1185453

ZN627
Zinc finger protein 627

1

3

High-throughput

0.445

High

1234204

ZN561
Zinc finger protein 561

1

4

High-throughput

0.445

High

1237361

ZN611
Zinc finger protein 611

1

4

High-throughput

0.445

High

1237415

ZN614
Zinc finger protein 614

1

1

High-throughput

0.445

High

1268298

ZN516
Zinc finger protein 516

1

4

Small-scale

0.445

High

1271998

RAD50
DNA repair protein RAD50

1

10

Small-scale

0.445

High

1289412

ZNF2
Zinc finger protein 2

1

1

High-throughput

0.445

High

1289413

ZN577
Zinc finger protein 577

1

3

High-throughput

0.445

High

1289454

ZFP57
Zinc finger protein 57 homolog

1

4

High-throughput

0.445

High

1289473

AGO1
Protein argonaute-1

1

2

High-throughput

0.445

High

1289475

ZN215
Zinc finger protein 215

1

4

High-throughput

0.445

High

608245

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

1

Small-scale

0.437

High

1127669

PRC2B
Protein PRRC2B

1

8

High-throughput

0.437

High

1262554

DNJB3
DnaJ homolog subfamily B member 3

1

4

High-throughput

0.437

High

1289431

DJC25
DnaJ homolog subfamily C member 25

1

4

High-throughput

0.437

High

1289461

SEP10
Septin-10

1

1

High-throughput

0.437

High

1282571

ZN566
Zinc finger protein 566

1

0

High-throughput

0.426

High

1032997

PLD1
Phospholipase D1

2

0

High-throughput

0.318

High

1289483

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

0

High-throughput

0.311

High

1238333

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low

1289479

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1087524

LAMA3
Laminin subunit alpha-3

1

0

Small-scale

0.269

Low

483711

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024