HitPredict

Interactor 1: TGFI1 (O43294)
Transforming growth factor beta-1-induced transcript 1 protein (Androgen receptor coactivator 55 kDa protein) (Androgen receptor-associated protein of 55 kDa) (Hydrogen peroxide-inducible clone 5 protein) (Hic-5)
Gene: TGFB1I1

Interactor 2: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	9858471
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 461 Hs			1 450
+	Hs
		782755 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		CSK_HUMAN (1-450): 0: 543: 100.00
+	Hs
		442845 FHL5_HUMAN (251-461): 1.49e-57: 193: 26.05		HCK_HUMAN (3-445): 6.38e-167: 481: 36.32
+	Hs
		782788 FHL2_HUMAN (199-337): 2.52e-24: 103: 23.78		CSK_HUMAN (1-450): 0: 543: 100.00
+	Hs
		337395 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		ABL1_HUMAN (5-447): 1.78e-164: 494: 37.83
+	Mm
		337635 PAXI_MOUSE (345-461): 2.61e-36: 143: 34.19		ABL1_MOUSE (5-447): 5.69e-165: 495: 37.83
+	Hs
		412085 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		FYN_HUMAN (12-442): 1.26e-170: 491: 36.77
+	Hs
		522857 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		SRC_HUMAN (12-442): 8.48e-171: 491: 39.33
+	Hs
		433288 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		YES_HUMAN (12-442): 5.99e-170: 490: 37.30
+	Mm
		403454 PAXI_MOUSE (345-461): 2.61e-36: 143: 34.19		SRC_MOUSE (12-442): 1.93e-169: 488: 39.55
+	Hs
		411641 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		LCK_HUMAN (5-443): 1.95e-168: 485: 38.55
+	Hs
		789046 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		ABL2_HUMAN (4-443): 1.63e-160: 485: 39.33
+	Hs
		442793 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		HCK_HUMAN (3-445): 6.38e-167: 481: 36.32
+	Hs
		111447 PDLI7_HUMAN (343-461): 4.25e-34: 134: 34.45		J3QRU1_HUMAN (12-442): 7.07e-170: 490: 37.30
+	Hs
		150505 ABLM1_HUMAN (277-461): 3.32e-42: 161: 27.55		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		433484 PDLI7_HUMAN (343-461): 4.25e-34: 134: 34.45		YES_HUMAN (12-442): 5.99e-170: 490: 37.30
+	Hs
		788959 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		MATK_HUMAN (7-440): 2.57e-161: 466: 53.79
+	Hs
		433646 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		LYN_HUMAN (4-445): 3.75e-160: 463: 37.12
+	Hs
		823358 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		BLK_HUMAN (8-445): 3.88e-159: 461: 37.03
+	Hs
		788979 PAXI_HUMAN (345-461): 8.93e-37: 144: 34.19		TEC_HUMAN (8-450): 6.4e-150: 442: 36.96
+	Hs
		442827 FHL2_HUMAN (199-337): 2.52e-24: 103: 23.78		HCK_HUMAN (3-445): 6.38e-167: 481: 36.32