Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 21150319
Identification Methods tandem affinity purification
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000165 - MAPK cascade
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0071456 - cellular response to hypoxia
GO:0140297 - DNA-binding transcription factor binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 606
Hs

1 454
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024