Interactor 1: M3K7 (O43318)
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (Transforming growth factor-beta-activated kinase 1) (TGF-beta-activated kinase 1)
Gene: MAP3K7

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 23472066, 20462248
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~PK_Tyr_Ser-Thr
Common GO terms GO:0000165 - MAPK cascade
GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 606
Hs

1 255
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024