HitPredict

Interactor 1: SYNJ1 (O43426)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Gene: SYNJ1

Interactor 2: PACN3 (Q9UKS6)
Protein kinase C and casein kinase substrate in neurons protein 3 (SH3 domain-containing protein 6511)
Gene: PACSIN3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11082044
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1573 Hs			1 424
+	Hs
		203251 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		PACN1_HUMAN (4-422): 1.04e-84: 267: 48.86
+	Hs
		203262 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		PACN2_HUMAN (4-422): 2.86e-77: 249: 48.96
+	Hs
		203224 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		MYO1E_HUMAN (2-422): 5.28e-39: 151: 14.03
+	Hs
		203228 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Hs
		203246 SYNJ1_HUMAN (1-1573): 0: 1356: 100.00		SH3Y1_HUMAN (308-419): 5.4e-12: 68.7: 24.78
+	Hs
		166049 SYNJ2_HUMAN (1-1418): 0: 1118: 41.56		ITSN1_HUMAN (30-424): 3.23e-15: 80.2: 10.78
+	Sc
		797818 INP52_YEAST (8-1175): 0: 828: 25.70		LSB3_YEAST (312-422): 8.67e-13: 71.8: 25.89
+	Sc
		797880 INP53_YEAST (33-1087): 0: 827: 26.72		LSB3_YEAST (312-422): 8.67e-13: 71.8: 25.89
+	Sc
		755683 INP53_YEAST (33-1087): 0: 827: 26.72		BZZ1_YEAST (1-248): 2.87e-12: 70.6: 19.17
+	Mm
		956956 SHIP1_MOUSE (505-1251): 6.64e-154: 502: 20.90		PPIP1_MOUSE (7-422): 4.83e-63: 210: 20.37
+	Hs
		1075809 SHIP1_HUMAN (505-1301): 1.21e-138: 461: 21.40		CIP4_HUMAN (16-365): 9.77e-38: 146: 17.05
+	Hs
		968134 OCRL_HUMAN (502-978): 5.31e-125: 415: 27.52		MYO1E_HUMAN (2-422): 5.28e-39: 151: 14.03